Sökning: "Jean-Yves Roignant"

Hittade 2 avhandlingar innehållade orden Jean-Yves Roignant.

1. 1. Canonical and non-canonical functions of METTL3 in breast cancer

   Författare :Cyrinne Achour; Francesca Aguilo; Jonathan D. Gilthorpe; Jean-Yves Roignant; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; RNA modification; METTL3; m6A; alternative splicing; exocyst; breast cancer;

   Sammanfattning : Gene expression is spatially and temporally regulated at multiple levels. N6-methyladenosine (m6A) is the most prevalent internal modification in messenger RNA (mRNA) and long noncoding RNA (lncRNAs). LÄS MER

3. 2. Chromosome-specific adaptations of RNA stability and the roles of the roX RNAs in dosage compensation

   Författare :Marie-Line Faucillion; Jan Larsson; Jean-Yves Roignant; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila melanogaster; dosage compensation; buffering; RNA stability; RNA decay; RNA half-life; RNA-seq; genome-wide; sex chromosomes; evolution; roX1; roX2; POF; MSL; molekylärbiologi; Molecular Biology;

   Sammanfattning : Sex chromosomes evolved from an ancient pair of autosomes and the Y chromosome lost most of its genetic information in the process. This created two kinds of genomic imbalances: the first one between males (XY) and females (XX) and the second one between the sex chromosomes and the autosomes (X:AA). LÄS MER