Sökning: "non-coding RNA"

Visar resultat 6 - 10 av 105 avhandlingar innehållade orden non-coding RNA.

1. 6. Evolution of protein and non-coding RNA genes studied with comparative genomics

   Författare :Marcela Davila Lopez; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bioinformatics; evolution; non-coding RNA; gene prediction; gene order; bidirectional promoter; homologue prediction; secondary structure; RNAse P; RNase MRP;

   Sammanfattning : The identification of protein and non-coding RNA (ncRNA) genes is one important step in the analysis of a genome. This thesis focuses on the identification and analysis of proteins and ncRNAs homologues by exploiting a variety of computational methods in order to reach conclusions as to their structure, function, evolution and regulation. LÄS MER

3. 7. iLocks: a novel tool for RNA assays with improved specificity

   Författare :Tomasz Krzywkowski; Mats Nilsson; Gunnar von Heijne; Weng-Onn Lui; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RNA; miRNA; non-coding RNA; padlock probes; rolling circle amplification; invader; single cell; in situ; adenovirus; virology; diagnostics; Biochemistry; biokemi;

   Sammanfattning : The Central Dogma of molecular biology describes a framework for how genetic information is transferred in cells, placing RNA as a messenger between DNA and translated proteins. During the last years, interest in RNA research has grown tremendously due to the increasing understanding and recognition of the importance of RNA in regulation of gene expression, biochemical catalysis, and genome integrity surveillance. LÄS MER

4. 8. Small non-coding RNA in early fly development : plasticity, interactions and improved bioinformatic tools

   Författare :Lovisa Örkenby; Anita Öst; Rashmi Ramesh; Daniel Nätt; Nicola Iovino; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Maternal-to-zygotic transition; sncRNA; miRNA; piRNA; Embryogenesis; Zygotic gene activation;

   Sammanfattning : At fertilization, the male and female pronuclei undergo a transformation from germline to pluripotency as they fuse, marking the beginning of Drosophila embryogenesis. As the parental contributions decrease, the zygote takes control of its genome in a process called the maternal-to-zygotic transition (MZT). LÄS MER

5. 9. Non-coding RNAs and Extracellular Vesicles in Cutaneous Squamous Cell Carcinoma

   Författare :Chen Li; Andor Pivarcsi; Gareth Inman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cutaneous squamous cell carcinoma; microRNA; long non-coding RNA; extracellular vesicle;

   Sammanfattning : Cutaneous squamous cell carcinoma (cSCC) ranks among the most widespread malignancies with metastatic potential. Investigating the molecular mechanism of tumorigenesis will enhance our understanding of cSCC. Aberrant expression of non-coding RNAs has been extensively reported in human cancers. LÄS MER

7. 10. Characterization of non-coding RNAs in cancer

   Författare :Per Johnsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : While originally though to only code for proteins, it now stands clear that RNA is a multifunctional molecule involved in a great variety of molecular processes. Recent advances in genome-wide platforms have revealed underappreciated roles of non-protein coding RNAs (ncRNAs). LÄS MER