Sökning: "nitric-oxide synthase"

Visar resultat 16 - 20 av 189 avhandlingar innehållade orden nitric-oxide synthase.

1. 16. Regulation of Insulin Secretion in Relation to Nitric Oxide, Carbon Monoxide and Acid alpha-Glucoside Hydrolase Activities

   Författare :Henrik Mosén; Lund Klinisk fysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endokrinologi; secreting systems; diabetology; Endocrinology; Medicin människa och djur ; Medicine human and vertebrates ; GK rat; insulin secretion; carbon monoxide; acid alpha-glucoside hydrolases; nitric oxide; heme oxygenase; isoforms of nitric oxide synthase; diabetologi; sekretion;

   Sammanfattning : The main stimulus for insulin secretion is elevated blood glucose levels. In this thesis the aim was to study less well-known systems involved in the complex regulation of glucose-stimulated insulin release, emphasizing the role of the lysosomal/vacuolar system and the associated glycogenolytic acid alpha-glucoside hydrolases, but also the HO-CO and NOS-NO systems. LÄS MER

3. 17. Nitric oxide modulates neutrophil function

   Författare :Tony Forslund; Per Venge; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : An important role of the neutrophils is to attack and destroy microbial intruders. In order to do so, these leukocytes must adhere to the blood vessel wall, pass through the endothelial cell layer, move through the tissues to the point of infection, ingest the intruder and destroy it. LÄS MER

4. 18. Electron and Proton Transfer in Nitric Oxide Reductase : NO Binding, NO Reduction and no Pumping

   Författare :Peter Lachmann; Pia Ädelroth; Peter Brzezinski; Fahmi Himo; Stockholms universitet; []
   Nyckelord :Flow-Flash; Nitric Oxide Reductase; Heme Copper Oxidase;

   Sammanfattning : Nitric oxide reductase (NOR) from Paracoccus denitrificans catalyzes the two electronreduction of NO to N2O (2NO + 2H+ + 2e- → N2O + H2O) as part of the process ofdenitrification, the step-wise reduction of nitrate to dinitogen. The NOR-catalyzedreaction is central in the nitrogen cycle, since in this step the N=N double bond isformed. LÄS MER

5. 19. Nitric oxide synthase in female reproductive and urinary organs: Hormonal regulation and functional significance

   Författare :Jassim Al-Hijji; Lund Obstetrik och gynekologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gynaecology; Obstetrics; estrogen; trophoblast; placenta; vagina; Nitric oxide; uterus; ovarian steroids; andrology; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

   Sammanfattning : Nitric oxide synthase (NOS) activity was studied in cytosolic and particulate fractions in reproductive organs from rabbit (uterus and vagina) and rat (uterus, vagina and cervix). NOS was found predominantly in cytosolic fractions in all tissues and the activity of NOS in both fractions was highly Ca2+ dependent. LÄS MER

7. 20. Hypoxic pulmonary vasoconstriction and nitric oxide

   Författare :Kristina Hambraeus Jonzon; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :hypoxia; pulmonary vasoconstriction; regional pulmonary bloodflow; stimulus-response; nitric oxide; blood-borne distant effects; nitric oxide synthase activity; inhaled; exhaled; non-enzymatic;

   Sammanfattning : Hypoxia causes pulmonary vasoconstriction (HPV), improving oxygenation by redistribution of the pulmonary blood flow to better oxygenated lung regions. HPV is intrinsic to the pulmonary vascular smooth muscle cell, but can be modulated by several vasoactive substances, as for example endothelium derived nitric oxide (NO) and endothelin-1 (ET-1). LÄS MER