Sökning: "lamivudine"

Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet lamivudine.

  1. 1. Drug Analysis Bioanalytical Method Development and Validation

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Mikaela Malm; Uppsala universitet.; [2008]
    Nyckelord :Analytical chemistry; African trypanosomiasis; calibration model; chiral chromatography; dried blood spots; eflornithine; evaporative light-scattering detection; HIV AIDS; lamivudine; liquid chromatography; malaria; nevirapine; piperaquine; pneumonia; solid-phase extraction; sulfadoxine; sulfamethoxazole; validation; zidovudine; Analytisk kemi;

    Sammanfattning : This thesis describes bioanalytical methods for drug determination in biological matrixes, with drugs in focus used against diseases largely affecting low-income countries.Solid-phase extraction is used for sample cleanup, and processed samples are analyzed by liquid chromatography. LÄS MER

  2. 2. Development and Validation of Bioanalytical Methods Application to Melatonin and Selected Anti-Infective Drugs

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Susanne Römsing; Uppsala universitet.; Högskolan Dalarna.; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry; NATURVETENSKAP Kemi; Analytical Chemistry; Analytisk kemi; african trypanosomiasis; melatonin; malaria; antiretroviral drugs; lumefantrine; tafenoquine; lamivudine; nevirapine; zidovudine; sampling paper; dried blood spots; capillary blood; antimalarial drugs; solid-phase extraction; liquid chromatography;

    Sammanfattning : This thesis describes bioanalytical methods for measuring melatonin and some anti-infective drugs in biological fluids. Solid-phase extraction (SPE) or protein precipitation was used for enrichment and purification of the analytes and Liquid Chromatography (LC) was used to analyze the samples. LÄS MER

  3. 3. Real-time PCR studies of genotypes, mutations and replication of hepatitis B virus

    Detta är en avhandling från Göteborg : University of Gothenburg

    Författare :Sebastian Malmström; Göteborgs universitet.; Gothenburg University.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hepatitis B virus; real-time PCR; lamivudine resistance; genotypes; replication;

    Sammanfattning : Infection with hepatitis B virus (HBV) is an important cause of liver disease and affects 350 million people worldwide, causing 600,000 deaths/year. Treatment includes interferon and nucleoside analogues (NAs) such as lamivudine, entecavir, and tenofovir. LÄS MER

  4. 4. Resistance to antiviral drugs in HIV and HBV

    Detta är en avhandling från Stockholm : Karolinska Institutet, Microbiology and Tumor Biology Center (MTC)

    Författare :Anna Lindström; Karolinska Institutet.; Karolinska Institutet.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; HBV; drug-resistance; Sanger sequencing; pyrosequencing;

    Sammanfattning : Development of resistance to antiviral drugs is a major problem in treatment of several viral infections including human immunodeficiency type 1 (HIV-1) and hepatitis B virus (HBV). Resistance may be the primary reason for treatment failure, but may also develop secondary to problems with adherence or pharmacokinetics. LÄS MER

  5. 5. Resolution of Dynamic Systems: Applications in Asymmetric Synthesis and Materials Science

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Lei Hu; KTH.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Kemi; Chemistry;

    Sammanfattning : This thesis is built on the concepts of constitutional dynamic chemistry and dynamic kinetic resolution, where reversible covalent reactions are used to generate dynamics and kinetically controlled reactions are employed for resolution. The thesis is divided into two parts:The first section focuses on the study of dynamic systemic resolution, a concept derived from constitutional dynamic chemistry. LÄS MER