Sökning: "chiral chromatography"

Visar resultat 1 - 5 av 44 avhandlingar innehållade orden chiral chromatography.

  1. 1. Adsorption Studies with Liquid Chromatography : Experimental Preparations for Thorough Determination of Adsorption Data

    Författare :Lena Edström; Jonas Bergquist; Lars Hagel; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; Liquid chromatography; HPLC; UHPLC; Reversed phase; Preparative chromatography; Adsorption isotherm; Injection profile; Sample pH; pH stable conditions; Peak deformation; Band distortion; Overloaded band; Chiral preparative chromatography; Analytical Chemistry; Analytisk kemi;

    Sammanfattning : Analytical chemistry is a field with a vast variety of applications. A robust companion in the field is liquid chromatography, the method used in this thesis, which is an established workhorse and a versatile tool in many different disciplines. LÄS MER

  3. 2. Packed Column Supercritical Fluid Chromatography : Applications in Environmental Chemistry

    Författare :Nicole Riddell; Bert van Bavel; Robert McCrindle; Ingrid Ericson Jogsten; Jake Ryan; Örebro universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Supercritical Fluid Chromatography; Mass Spectrometry; Ionization; POPs; APPI; APCI; chiral; achiral; packed column;

    Sammanfattning : Although gas and liquid chromatography have emerged as dominant separation techniques in environmental analytical chemistry, these methods do not allow for the concurrent analysis of chemically diverse groups of persistent organic pollutants (POPs). There are also a small number of compounds which are not easily amenable to either of these traditional separation techniques. LÄS MER

  4. 3. Aspects of Porous Graphitic Carbon as Packing Material in Capillary Liquid Chromatography

    Författare :Anna Törnkvist; Wolfgang Lindner; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; PGC; porous graphitic carbon; stationary phase; packing material; LC; liquid chromatography; miniaturized; chiral; enantiomer; ESI; electrospray ionization; mass spectrometry; polar compounds; L-DOPA; dopamine; biological samples; biological matrix; Analytisk kemi; PGC; poröst grafitiserat kol; stationärfas; packningsmaterial; LC; vätskekromatografi; miniatyriserade system; kiral; enantiomer; ESI; electrospray jonisation; mass spektrometri; polära föreningar; L-DOPA; dopmamine; biologiska prover; biologisk matris; Analytical chemistry; Analytisk kemi; Analytical Chemistry; Analytisk kemi;

    Sammanfattning : In this thesis, porous graphitic carbon (PGC) has been used as packing material in packed capillary liquid chromatography. The unique chromatographic properties of PGC has been studied in some detail and applied to different analytical challenges using both electrospray ionization-mass spectrometry (ESI-MS) and ultra violet (UV) absorbance detection. LÄS MER

  5. 4. Drug Analysis : Bioanalytical Method Development and Validation

    Författare :Mikaela Malm; Yngve Bergqvist; Anders Colmsjö; Uppsala universitet; []
    Nyckelord :Analytical chemistry; African trypanosomiasis; calibration model; chiral chromatography; dried blood spots; eflornithine; evaporative light-scattering detection; HIV AIDS; lamivudine; liquid chromatography; malaria; nevirapine; piperaquine; pneumonia; solid-phase extraction; sulfadoxine; sulfamethoxazole; validation; zidovudine; Analytisk kemi;

    Sammanfattning : This thesis describes bioanalytical methods for drug determination in biological matrixes, with drugs in focus used against diseases largely affecting low-income countries. Solid-phase extraction is used for sample cleanup, and processed samples are analyzed by liquid chromatography. LÄS MER

  7. 5. New Techniques for Chiral Separations

    Författare :Jeanette Olsson; Lars Blomberg; Steen Honoré Hansen; Karlstads universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; analytical chemistry; chiral separation; GC; CE; CEC; Analytical chemistry; Analytisk kemi; Kemi; Chemistry;

    Sammanfattning : Gas chromatography (GC) has been utilized for the study of enantiomer resolution of the atropisomers of PCBs, o,p´-DDD and o,p´-DDT. Different substituents and concentrations of cyclodextrin, capillary dimensions and type of stationary phase films have been investigated to achieve the resolution of as many of the atropisomers on one column as possible. LÄS MER