Sökning: "capillary blood"
Visar resultat 1 - 5 av 150 avhandlingar innehållade orden capillary blood.
1. Nanoparticle-based capillary electrochromatography
Sammanfattning : This thesis concerns a highly efficient nanoparticle-based capillary electrochromatography separation technique and its coupling with mass spectrometric detection. From chromatographic theory, it is well known that the separation efficiency increases with decreasing particle size. LÄS MER
2. Capillary driven devices for patient-centric diagnostics
Sammanfattning : Lateral flow assays is an example of a successful microfluidic platform relying on passive fluid transport, making them suitable for patient-centric and point-of-care applications. Flow control and valving in capillary driven devices typically rely on design-imprinted functions and operations which can be a limiting factor. LÄS MER
3. Bioanalysis using capillary electrophoresis and mass spectrometry : Applied on proteins, protein nanofibrils and polyvinyl alcohol microbubbles
Sammanfattning : The sequencing of the genome of various species, including the human species, have led to increased understanding about how a protein structure is generated, and how specific structures are related to the proteins’ functionality. In paper I and II of this thesis, the folding of proteins in vitro to form hierarchical nanostructures, which in vivo often have a pathological effect, have been studied. LÄS MER
4. Mechanisms of transendothelial and tissue transport in the peritoneum. Experimental studies on rat
Sammanfattning : In the present thesis, the quantitative role of active transport (transcytosis) in bulk transvascular protein movement in vivo was evaluated. Using chemical transcytosis inhibition (N-ethylmaleimide (NEM) and filipin), we were able to show that NEM actually increases endothelial permeability to macromolecules, probably as a result of unspecific toxic action on endothelial cells. LÄS MER
5. Capillary and interstitial transport of fluid and solutes across the peritoneal membrane
Sammanfattning : According to the three-pore model of peritoneal transport the major exchange pathway between the blood and the peritoneal cavity is represented by “small pores”, permeable to small solutes and water. Osmotically induced fluid flow, as during peritoneal dialysis (PD), is postulated to occur to a great extent through a water-only pathway, whereas proteins are predicted to reach the peritoneal cavity by unidirectional convection across “large pores”. LÄS MER