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Visar resultat 1 - 5 av 347 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Exposure to brominated flame retardants in electronics recycling : air and human plasma levels

   Författare :Anneli Julander; Magnus Engwall; Bert van Bavel; Myrto Petreas; Örebro universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; PBDE; BTBPE; DeBDethane; Thyroid hormone; Occupational exposure; Human plasma; Air sampling; MeO-PBDE; PBDE; BTBPE; DeBDetan; Sköldkörtelhormon; Yrkesexponering; Human plasma; Luftprovtagning; MeO-PBDE; Environmental engineering; Miljöteknik; Enviromental Science; Miljövetenskap;

   Sammanfattning : Polybrominated diphenyl ethers (PBDEs), 1,2-bis(2,4,6-tribromophenoxy)ethane (BTBPE) and 1,2-bis(2,3,4,5,6-pentabromophenyl)ethane (DeBDethane) were analysed in air and blood samples from workers at an electronics recycling facility. The samples were collected regularly for 18 months and were analysed by isomer specific GC/MS analysis in both electron impact (EI) and negative chemical ionisation (NCI) mode. LÄS MER

3. 2. Multiplexed absolute quantification of blood plasma proteins using targeted proteomics

   Författare :David Kotol; Mathias Uhlén; Edfors Fredrik; Roman Zubarev; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mass spectrometry; targeted proteomics; stable isotope standards; recombinant protein standards; absolute quantification; blood plasma; multiplex analysis; plasma profiling; Biotechnology; Bioteknologi;

   Sammanfattning : Proteins are the molecular building blocks of all living organisms. They are the functioning actors in metabolism and communication, and they give specific architecture and purpose to all tissues. Their abundance is dynamic and can be interpreted and associated to different physiological states or diseases. LÄS MER

4. 3. Human Adipocytes : Proteomic Approaches

   Författare :Åsa Jufvas; Peter Strålfors; Alexander Vener; Maria V Turkina; Hans Jörnvall; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Type 2 diabetes is characterized by increased levels of glucose in the blood originating from insulin resistance in insulin sensitive tissues and from reduced pancreatic insulin production. Around 400 million people in the world are diagnosed with type 2 diabetes and the correlation with obesity is strong. LÄS MER

5. 4. Mitochondrial function in sepsis - Temporal evolvement of respiratory capacity in human blood cells

   Författare :Fredrik Sjövall; Lund Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human; sepsis; severe sepsis; septic shock; platelets; mitochondria; OXPHOS; high-resolution respirometry; mitochondrial disorders; multiple organ failure; biogenesis; leukocytes; cytokines; respirometry; oxygen consumption; blood cells; temporal;

   Sammanfattning : Sepsis is a devastating disease that is caused by the host’s response to an overwhelming infectious process. As sepsis progresses, organs distant from the site of infection become affected and sepsis-induced multiple organ failure ensues. LÄS MER

7. 5. Qualitative and Quantitative Assessment of Cytochromes P450 mRNA in Human : Studies in the Liver, Blood and Gastrointestinal Mucosa

   Författare :Mari Thörn; Lars Lööf; Anders Rane; Ellen Vinge; Uppsala universitet; []
   Nyckelord :Medical sciences; cytochrome P450; CYP1A2; CYP1B1; CYP2E1; CYP3A4; CYP3A5; P-gp; gene expression; RT-PCR; liver; blood; gastrointestinal mucosa; MEDICIN OCH VÅRD; MEDICINE; MEDICIN;

   Sammanfattning : Drugs and other foreign compounds must often be metabolised before they can be excreted from the body. One enzyme system that is responsible for this is the cytochrome P450 gene family (CYP). LÄS MER