Sökning: "Thyroid hormone"

Visar resultat 1 - 5 av 121 avhandlingar innehållade orden Thyroid hormone.

  1. 1. Life without thyroid hormone receptors

    Författare :Sten Göthe; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Thyroid hormone (TH) has many important functions during development and in the adult individual. It reaches its target cells via the blood system and binds its receptor (TR) located within the cell nucleus where the receptor regulates target genes. This hormone-mediated gene regulation is a finely tuned interplay of numerous parameters. LÄS MER

  3. 2. Regulation of postnatal neurogenesis and brain angiogenesis by thyroid hormone

    Författare :Jenny Liqun Zhang; Göteborgs universitet; []
    Nyckelord :thyroid hormone; neurogenesis; angiogenesis; SVZ OB; hippocampus; neural stem cells; endothelial cells; astrocytes;

    Sammanfattning : Thyroid hormone (TH), which is secreted by the thyroid gland, exerts significant effects on the central nervous system (CNS), especially during development, so that delayed treatment of perinatal hypothyroidism results in severe cognitive retardation. Continuous postnatal neurogenesis occurs throughout adulthood in the subventricular zone (SVZ) of the lateral ventricle wall and in the subgranular zone (SGZ) of the dentate gyrus (DG) of the hippocampal formation. LÄS MER

  4. 3. In vivo- and in vitro-studies of hormonal regulation of cytosolic glutathione transferases : effects of growth hormone, adrenocorticotrophic hormone, thyroid hormone and testosterone

    Författare :Louise Staffas; Tim Mantle; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : .... LÄS MER

  5. 4. Affective disorders and their treatments : implications for thyroid function

    Författare :Ingrid Lieber; Ursula Werneke; Michael Ott; Mats Eliasson; John McGrath; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bipolar disorder; affective disorder; lithium; thyroid dysfunction; hyperthyroidism; hypothyroidism; Delphi-consensus; psykiatri; Psychiatry;

    Sammanfattning : BackgroundThe relationship between affective disorders, mood-stabilisers and thyroid dysfunction is complex and poorly understood. Symptoms of thyroid dysfunction can overlap with symptoms of affective disorder, destabilise mood, and impact physical health. LÄS MER

  7. 5. Regulation of apoptosis in the thyroid epithelium

    Författare :Abeba Demelash; Göteborgs universitet; []
    Nyckelord :Thyroid; Apoptosis; Caspase; Calpain; Hydrogen peroxide; TGF-beta; Staurosporine; Selenium; Cytochrome c;

    Sammanfattning : Apoptosis or programmed cell death allows the multicellular organism to remove cells that are in excess or potentially dangerous. Apoptosis has to be strictly controlled, yet inappropriately activated or suppressed apoptototic may contribute to a variety of diseases, including cancer, autoimmune disorders and neurodegenerative conditions. LÄS MER