Sökning: "heme A"

Visar resultat 6 - 10 av 142 avhandlingar innehållade orden heme A.

  1. 6. Porphyrins and heme in microorganisms : Porphyrin content and its relation to phototherapy and antimicrobial treatments in vivo and in vitro

    Författare :Jonas Fyrestam; Conny Östman; Jonas Bergquist; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Porphyrins; heme; phototherapy; antimicrobial resistance; singlet oxygen; photosensitizer; bacteria; HPLC-MS MS; oral bacteria; Aggregatibacter actinomycetemcomitans; Porphyromonas gingivalis; Escherichia coli; Analytical Chemistry; analytisk kemi;

    Sammanfattning : One of the greatest threats to human health is increasing antimicrobial resistance among pathogens, and finding alternatives for treatment of bacterial infections is of highest importance together with a more controlled use of antibiotics. Porphyrins and heme have both been shown to be a promising class of compounds for inactivation of bacteria; porphyrins by their excellent properties to act as a photosensitizer, and heme by its importance as an iron source during a bacterial infection in vertebrates. LÄS MER

  2. 7. Role of respiratory supercomplexes : Electronic connection between complexes III and IV

    Författare :Agnes Moe; Peter Brzezinski; James A. Letts; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; electron transfer; cytochrome c oxidase; cytochrome bc1; respiratory supercomplex; bioenergetics; membrane protein; biokemi; Biochemistry;

    Sammanfattning : In the final step of cellular respiration, electrons are transferred through the respiratory chain to reduce molecular oxygen to water. The energy released in this chain is used to maintain a proton electrochemical gradient across the cell membrane, which is used, for example, by the ATP synthase to produce ATP. LÄS MER

  3. 8. Studies on spinach plastocyanin and mutants : Expression in Escherichia coli, folding and function

    Författare :Mikael Ejdebäck; Örjan Hansson; Miguel A. De la Rosa; Göteborgs Universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; plastocyanin; electron transfer; copper; protein-protein interactions; protein expression; folding; site-directed mutagenesis; NMR; Naturvetenskap; Natural sciences;

    Sammanfattning : Photosynthesis is a process in which photons from sunlight excite chlorophylls in the thylakoid membranes of plants, algae and cyanobacteria. The photo-oxidised reaction centre chlorophyll P700 is re-reduced by an electron transferred from the soluble, blue copper protein plastocyanin. LÄS MER

  4. 9. Alpha-1-microglobulin, heme-binding protein, reductase and antioxidant

    Författare :Maria Allhorn; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reduction; inflammation; chronic ulcers; collagen; low density lipoproteins; Medicin människa och djur ; Medicine human and vertebrates ; antioxidation; heme; hemoglobin; alpha-1-microglobulin; lipocalin;

    Sammanfattning : This thesis describes structural and functional studies of alpha-1-microglobulin (a1m), a 26 kDa plasma and tissue protein that is evolutionarily well-conserved and belongs to the lipocalin superfamily. The lipocalins are polypeptides of 160-190-amino acids that are folded into an 8-stranded beta-barrel forming a pocket with a hydrophobic interior. LÄS MER

  5. 10. Choreography of a proton pump : Studies of charge-transfer reactions in cytochrome c oxidase

    Författare :Jóhanna Vilhjálmsdóttir; Peter Brzezinski; Joachim Heberle; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; heme-copper oxidase; cytochrome c oxidase; respiration; proton pump; electron transfer; proton transfer; proton-transfer pathway; midpoint potential; proton-pumping mechanism; Biochemistry; biokemi;

    Sammanfattning : In the last step of cellular respiration, electrons from metabolites are transferred to molecular oxygen, mediated by the enzyme complexes of the respiratory chain. Some of these enzyme complexes couple these redox reactions to formation of an electrochemical proton gradient across the cell membrane. The proton gradient is used e.g. LÄS MER