Sökning: "low density lipoproteins"

Visar resultat 1 - 5 av 69 avhandlingar innehållade orden low density lipoproteins.

1. 1. Low-Density Lipoprotein Oxidation and Renal Dysfunction : New Markers of Poor Prognosis in Patients with Unstable Coronary Artery Disease

   Författare :Nina Johnston; Lars Wallentin; Tomas Jernberg; Agneta Siegbahn; Lena Jonasson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; myocardial infarction; unstable angina; oxidized low-density lipoprotein; renal function; prognosis; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

   Sammanfattning : In patients with unstable coronary artery disease (CAD) biochemical markers are emerging as useful tools in clinical management. In this thesis we studied the use of markers of low-density lipoprotein (LDL) oxidation and renal function. LÄS MER

3. 2. Studies of atherogenic lipoproteins using mass spectrometry-based lipidomics

   Författare :Marcus Ståhlman; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lipids; lipoproteins; atherogenesis; lipidomics; type 2 diabetes; mass spectrometry;

   Sammanfattning : The prevalence of type 2 diabetes is increasing worldwide and is about to reach epidemic proportions. The disease is often associated with dyslipidemia which is characterized by an atherogenic lipoprotein profile including elevated serum triacylglycerol levels, low high-density lipoprotein levels and high levels of small low-density lipoproteins. LÄS MER

4. 3. Model Membranes and Their Interactions with Native and Artificial Lipoproteins

   Författare :Sarah Waldie; Marité Cárdenas; Michael Haertlein; Selma Maric; Timothy Dafforn; Malmö universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Model Cell Membranes; Cholesterol; Lipoproteins; Apolipoprotein E; Lipid Exchange; Reconstituted HDL; Atherosclerosis; Deuteration; Neutron Reflectometry; Small-Angle Neutron Scattering;

   Sammanfattning : Atherosclerosis arises from build-up of plaque in the blood, can result in cardiovascular disease and is the largest killer in the west. Low- and high-density lipoproteins are involved in the disease development by depositing and removing lipids to and from artery walls. LÄS MER

5. 4. Proteoglycans, group IIA phospholipase A2, and lipoproteins.Potential involvement in atherogenesis

   Författare :Peter Sartipy; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atherosclerosis; group IIA phospholipase A2; proteoglycans; lipoproteins; inflammation;

   Sammanfattning : Atherosclerosis is a multifactorial complex disease characterized by a focal accumulation of ApoB-100 containing lipoproteins, extracellular matrix (ECM), and cells in the arterial intima accompanied by an inflammatory reaction. In vivo and in vitro data supports the hypothesis that sulfated extracellular proteoglycans may be responsible for the selective retention of low density lipoproteins (LDL) in the arterial wall. LÄS MER

7. 5. Interaction of Triglyceride-rich Lipoproteins with Platelets and Vitamin K-dependent Coagulation Factors

   Författare :Ning Xu; Avdelningen för klinisk kemi och farmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Triglycerides.; Prothrombin; Protein S; Protein C; Platelets; Phospholipids; Metabolism; Lipoproteins; Lipids; Endocytosis; Electron microscopy; Cytochemistry; Coronary heart disease; Blood coagulation factors; Arachidonic acid; Atherosclerosis; Clinical chemistry; Klinisk kemi; Haematology; extracellular fluids; Hematologi; extracellulära vätskor;

   Sammanfattning : 1. During incubation of platelets with 3H-arachidonic acid (20:4, n-6) and 14C-cholesterol doubly labelled and colloidal gold labelled chylomicrons (CMs) and chylomicron remnants (CMRs) CMs were taken up more efficiently than CMRs. Addition of unlabelled CMs, VLDLs, LDLs and HDLs decreased the uptake of labelled CMs. LÄS MER