Sökning: "silent synapse"

Hittade 4 avhandlingar innehållade orden silent synapse.

  1. 1. Plasticity of the developing glutamate synapse in the hippocampus

    Författare :Therése Abrahamsson; Göteborgs universitet; []
    Nyckelord :synaptic plasticity; long-term potentiation; short-term potentiation; silent synapse; development; hippocampus; glutamate;

    Sammanfattning : Synapses are highly plastic, i.e. they have the ability to change their signaling strength both in the short- and long-term (e.g. LÄS MER

  3. 2. Differences in glutamatergic transmission onto interneurons and pyramidal cells in the rat hippocampus

    Författare :Ilse Riebe; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AMPA; development; glutamate transmission; hippocampus; interneuron; NMDA; synapse;

    Sammanfattning : In the human brain there are about 100 billion excitatory glutamatergic neurons and 10 billion inhibitory GABAergic neurons. During development, these neurons are synaptically wired together into neural networks, functionally prepared to perform the full register of brain functions, and to learn from experiences. LÄS MER

  4. 3. Developmental plasticity of the glutamate synapse: Roles of low frequency stimulation, hebbian induction and the NMDA receptor

    Författare :Joakim Strandberg; Göteborgs universitet; []
    Nyckelord :AMPA receptor; Development; Glutamate; Hippocampus; Long-term depression; Long-term potentiation; NMDA receptor; Synaptic depression;

    Sammanfattning : The glutamate synapse is by far the most common synapse in the brain and acts via postsynaptic AMPA, NMDA and mGlu receptors. During brain development there is a continuous production of these synapses where those partaking in activity resulting in neuronal activity are subsequently selected to establish an appropriate functional pattern of synaptic connectivity while those that do not are elimimated. LÄS MER

  5. 4. Beyond AMPA and NMDA: Slow synaptic mGlu/TRPC currents : Implications for dendritic integration

    Författare :Marcus Petersson; Erik Fransén; Abdel El Manira; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; transient receptor potential; TRP; metabotropic glutamate receptor; mGlu1 5; dendritic integration; synaptic activation; temporal summation; low-frequency; entorhinal cortex; mathematical model; computational neuroscience; Computer science; Datavetenskap;

    Sammanfattning : In order to understand how the brain functions, under normal as well as pathological conditions, it is important to study the mechanisms underlying information integration. Depending on the nature of an input arriving at a synapse, different strategies may be used by the neuron to integrate and respond to the input. LÄS MER