Sökning: "Reporter"

Visar resultat 1 - 5 av 335 avhandlingar innehållade ordet Reporter.

  1. 1. Reporterskap – äventyr, irrbloss, dygder : Studie av en yrkespraxis

    Författare :Inger Orre; Bo Göranzon; Ingela Josefson; Jens-Ivar Nergaard; Sweden Stockholm Kungliga Tekniska Högskolan; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Reporter; journalistik; yrkespraxis; praktisk kunskap; mediepraktik; etik;

    Sammanfattning : .... LÄS MER

  3. 2. Development of sensitive cellular assay systems and their application to the identification of "orphan" seven-transmembrane receptors

    Författare :Knut Kotarsky; Slemhinnans immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biokemi; Metabolism; Biochemistry; metabolism; leukotrieneB4; thiazolidinedione; 9-HODE; fatty acid; luciferase; GFP; reporter gene; preclinical assay; receptor; GPCR;

    Sammanfattning : Seven-transmembrane, G-protein coupled receptors play a central role in physiology since they facilitate cell communication in multicellular organisms by recognition of a broad range of ligands. They also represent important drug targets. LÄS MER

  4. 3. The type I-E CRISPR-Cas system : Biology and applications of an adaptive immune system in bacteria

    Författare :Lina Amlinger; Magnus Lundgren; Peter Fineran; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; CRISPR; CRISPR-Cas; virus defense; bacteria; bacteriophage; adaptation; spacer integration; interference; gene silencing; fluorescent reporter; Escherichia coli; Mikrobiologi; Microbiology;

    Sammanfattning : CRISPR-Cas systems are adaptive immune systems in bacteria and archaea, consisting of a clustered regularly interspaced short palindromic repeats (CRISPR) array and CRISPR associated (Cas) proteins. In this work, the type I-E CRISPR-Cas system of Escherichia coli was studied.CRISPR-Cas immunity is divided into three stages. LÄS MER

  5. 4. Microplastics in the marine environment and the assessment of potential adverse effects of associated chemicals

    Författare :Christine Schönlau; Anna Kärrman; Magnus Engwall; Magnus Breitholtz; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microplastics; reporter gene bioassays; sorption; HOCs; polyethylene; polypropylene; polystyrene;

    Sammanfattning : During the last decade plastics have gained interest by scientists as emerging pollutants particularly in the marine environment due to their ubiquity and persistence. While several studies report the occurrence of microplastics in surface waters globally, there are no harmonized methods to sample and measure microplastics, and the knowledge of toxicological effects in the marine ecosystem is scarce. LÄS MER

  7. 5. Characterization of human dopaminergic neurons in the developing mesencephalon and upon differentiation of stem cells- for replacement therapy in Parkinson´s disease

    Författare :Jenny Nelander Wahlestedt; Utvecklings- och regenerativ neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson´s disease; stem cells; ventral mesencephalon; dopaminergic neurons; cell replacement therapy; human fetal tissue; radial glia; microRNA; BAC recombineering; reporter cell lines;

    Sammanfattning : Cell-replacement therapy is a promising approach for treating patients with Parkinson ́s disease (PD). For this purpose, there is a need for developing a protocol that can generate high numbers of human transplantable mesencephalic dopaminer- gic (mesDA) neurons. LÄS MER