Sökning: "drug use"

Visar resultat 26 - 30 av 1168 avhandlingar innehållade orden drug use.

1. 26. Polisen och narkotikaproblemet : från nationella aktioner mot narkotikaprofitörer till lokala insatser för att störa missbruket

   Författare :Anders Kassman; Hans Klette; Stockholms universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; abuse; addiction; control; drugs; media; moral panic; narcotics; the penal law on narcotics; organization; police; policy; prosecutor general; repression; Sweden; street dealer; time-series; TV; telephone-tapping; Sociology; sociologi; SOCIAL SCIENCES;

   Sammanfattning : The subject of this study is the policing of the drug problem during the period between the nationalization of the police force in 1965 and the introduction of imprisonment as a penalty for drug consumption in 1993. The influence of four key factors are discussed: legislation, organization, the conception of and the attention paid to the drug problem. LÄS MER

3. 27. Teenage Kicks – The Differential Development of Drug Use, Drunkenness, and Criminal Behaviour in Early to Mid-Adolescence

   Författare :Russell Turner; Göteborgs universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Drug use; Drunkenness; Alcohol intoxication; Criminal behaviour; Delinquency; Adolescence; Adolescent development; Risk behaviour; Risk factor; Prevention; Critical realism; realist method; Person-oriented method;

   Sammanfattning : This thesis studies the development of drug use, drunkenness, and criminal behaviour in early to mid-adolescence. Its main aims are to improve knowledge about how and why these three behaviours develop and to contribute towards the development of theory that can have applications in prevention policy and practice. The thesis comprises four studies. LÄS MER

4. 28. Pharmacokinetic, efficacy and safety modeling of new treatments against drug-resistant tuberculosis

   Författare :Lénaïg Tanneau; Mats Karlsson; Elin Svensson; Italo Poggesi; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacokinetics; pharmacodynamics; pharmacometrics; nonlinear mixed effect models; tuberculosis; drug-resistance; bedaquiline; delamanid; metabolite; drug-drug interactions; QTc interval; transaminases; time-to-positivity; Farmaceutisk vetenskap; Pharmaceutical Science;

   Sammanfattning : Tuberculosis (TB) is an ancient infectious disease that remains one of the greatest killers on the planet. Its eradication is impeded by the development of resistance to first-line treatment. Each year half a million patients are infected with drug-resistant (DR) TB. LÄS MER

5. 29. Computational and Experimental Models for the Prediction of Intestinal Drug Solubility and Absorption

   Författare :Christel A. S. Bergström; Per Artursson; Han van de Waterbeemd; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; aqueous drug solubility; melting point; intestinal drug permeability; pH-dependent solubility; multivariate data analysis; molecular descriptors; molecular surface area; in silico modeling; drug absorption; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

   Sammanfattning : New effective experimental techniques in medicinal chemistry and pharmacology have resulted in a vast increase in the number of pharmacologically interesting compounds. However, the number of new drugs undergoing clinical trial has not augmented at the same pace, which in part has been attributed to poor absorption of the compounds. LÄS MER

7. 30. Potentially inappropriate drug treatment among older people with cognitive impairment

   Författare :Eva Sönnerstam; Maria Gustafsson; Maria Sjölander; Hugo Lövheim; Ylva Böttiger; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Older people; major neurocognitive disorder; cognitive impairment; potentially inappropriate medications; drug-drug interactions; renal function; adverse drug reactions; nursing homes; time trends; Clinical Pharmacology; klinisk farmakologi;

   Sammanfattning : Background: The aging process contributes to alterations in organ systems, which lead to an increased risk for chronic conditions. Drug treatment is an important strategy in the management of chronic conditions; however, pharmacokinetic and pharmacodynamic alterations contribute to increased sensitivity to drug effects. LÄS MER