Sökning: "Italo Poggesi"

Hittade 1 avhandling innehållade orden Italo Poggesi.

1. 1. Pharmacokinetic, efficacy and safety modeling of new treatments against drug-resistant tuberculosis

   Författare :Lénaïg Tanneau; Mats Karlsson; Elin Svensson; Italo Poggesi; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacokinetics; pharmacodynamics; pharmacometrics; nonlinear mixed effect models; tuberculosis; drug-resistance; bedaquiline; delamanid; metabolite; drug-drug interactions; QTc interval; transaminases; time-to-positivity; Farmaceutisk vetenskap; Pharmaceutical Science;

   Sammanfattning : Tuberculosis (TB) is an ancient infectious disease that remains one of the greatest killers on the planet. Its eradication is impeded by the development of resistance to first-line treatment. Each year half a million patients are infected with drug-resistant (DR) TB. LÄS MER