Sökning: "klinisk farmakologi"

Visar resultat 1 - 5 av 317 avhandlingar innehållade orden klinisk farmakologi.

  1. 1. Use of secondary preventive drugs after stroke

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Maria Sjölander; Umeå universitet.; Umeå universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stroke; secondary prevention; drug use; equality; medication adherence; medication beliefs; medicin; Medicine; klinisk farmakologi; Clinical Pharmacology; samhällsfarmaci; Social Pharmacy;

    Sammanfattning : Background Stroke is a serious condition that can have significant impact on an individual’s health and is a significant burden on public health and public finances. Secondary preventive drug treatment after stroke is important for decreasing the risk of recurrent strokes. LÄS MER

  3. 2. Vardenafil and methylarginines in pulmonary hypertension

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Anna Sandqvist; Umeå universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vardenafil; pulmonary hypertension; pharmacokinetics; haemodynamics; right heart catheterization; adenosine; dimethylarginines; phosphodiesterase type 5 inhibitors; endothelin receptor antagonists; klinisk farmakologi; Clinical Pharmacology;

    Sammanfattning : Background: Pulmonary hypertension (PH) is a rare condition characterized by endothelial dysfunction and vascular remodelling, leading to increased pulmonary vascular resistance (PVR) and right ventricular heart failure. Endothelial dysfunction is associated with an imbalance between vasoconstrictor compounds, such as endothelin and thromboxane A2, and vasodilator compounds, such as prostacyclin and nitric oxide (NO). LÄS MER

  4. 3. Fatty acid amide hydrolase - A target for anti-inflammatory therapies?

    Detta är en avhandling från Umeå : Farmakologi och klinisk neurovetenskap

    Författare :Sandra Holt; Umeå universitet.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; FAAH; anandamide; endocannabinoid; pH; inflammation; NSAID; Farmakologi; MEDICINE Physiology and pharmacology Pharmacological research; MEDICIN Fysiologi och farmakologi Farmakologisk forskning; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Anti-inflammatory drugs are a widely used class of therapeutic agents, but the use of non-steroidal anti-inflammatory drugs (NSAID) is hampered by their gastrointestinal side-effects. Recent reports that cyclooxygenase-2 inhibitors may cause cardiovascular events underline the importance of identifying new therapeutic strategies for the treatment of inflammation. LÄS MER

  5. 4. Pharmacology of Palmitoylethanolamide and Related Compounds

    Detta är en avhandling från Umeå : Farmakologi och klinisk neurovetenskap

    Författare :Kent-Olov Jonsson; Umeå universitet.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; anandamide; cannabinoid; FAAH; palmitoylethanolamide; palmitoylisopropylamide; inflammation; mast cells; Farmakologi; MEDICINE Physiology and pharmacology Pharmacological research; MEDICIN Fysiologi och farmakologi Farmakologisk forskning; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Anandamide (AEA) is an endogenous fatty acid which activates the same cannabinoid receptors as ∆9-tetrahydrocannabinol, the psychoactive substance in marijuana. In vivo, anandamide exerts a number of actions including effects upon pain and inflammation. LÄS MER

  7. 5. 5-HT2A a serotonin receptor with a possible role in joint diseases

    Detta är en avhandling från Umeå : Umeå Universitet

    Författare :Anders Kling; Umeå universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 5-HT2A serotonin receptor; serotonin; rheumatoid arthritis; adverse drug reaction; HTR2A; glucocorticoids; klinisk farmakologi; Clinical Pharmacology;

    Sammanfattning : BackgroundSerotonin (5-HT), an amino acid derivative and neurotransmitter, has for long been studied in relation to inflammation. It is an endogenous ligand for several different types of serotonin receptors. The serotonin receptor 5-HT2A has been reported to have a role in the pathophysiology of arthritis in animal experiment models. LÄS MER