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Visar resultat 1 - 5 av 76 avhandlingar som matchar ovanstående sökkriterier.
1. Genome-wide Characterization of RNA Expression and Processing
Sammanfattning : The production of fully mature protein-coding transcripts is an intricate process that involves numerous regulation steps. The complexity of these steps provides the means for multilayered control of gene expression. LÄS MER
2. Analysis of RNA and DNA sequencing data : Improved bioinformatics applications
Sammanfattning : Massively parallel sequencing has rapidly revolutionized DNA and RNA research. Sample preparations are steadfastly advancing, sequencing costs have plummeted and throughput is ever growing. This progress has resulted in exponential growth in data generation with a corresponding demand for bioinformatic solutions. LÄS MER
3. Endogenous Retroviral RNA Expression in Humans
Sammanfattning : Human endogenous retroviruses (HERVs) constitute about 8% of the human genome. There are around 4000 pol-containing retroviral integrations in the human genome, which makes it impractical to measure each of them separately. LÄS MER
4. Chromosome-specific adaptations of RNA stability and the roles of the roX RNAs in dosage compensation
Sammanfattning : Sex chromosomes evolved from an ancient pair of autosomes and the Y chromosome lost most of its genetic information in the process. This created two kinds of genomic imbalances: the first one between males (XY) and females (XX) and the second one between the sex chromosomes and the autosomes (X:AA). LÄS MER
5. Differential RNA expression in benign and malignant adrenocortical tumours
Sammanfattning : Adrenocortical cancer is a rare but very aggressive endocrine tumor, with a yearly incidence of 0.5 to 2 cases per million inhabitants, accounting for 0.2% of all cancer related deaths. LÄS MER