Sökning: "cDNA"

Visar resultat 1 - 5 av 286 avhandlingar innehållade ordet cDNA.

  1. 1. Computational approaches for in-depth analysis of cDNA sequence tags

    Författare :Per Unneberg; Joakim Lundberg; Leif Andersson; KTH; []
    Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; Biotechnology; cDNA; EST; gene expression; SNP; SAGE; polymorphism; Bioteknik; Bioengineering; Bioteknik;

    Sammanfattning : Major recent improvements in biotechnology have led to an accelerated production of DNA sequences. The completion of the human genome sequence, along with the genomes of more than two hundred other species, has marked the arrival of the genome era. The ultimate goal is to understand the structure and function of genomes and their genes. LÄS MER

  2. 2. Structure and organization of genes for the predominant seminal plasma proteins semenogelin I, semenogelin II and beta-microseminoprotein

    Författare :Magnus Ulvsbäck; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical chemistry; transglutaminase substrate; semen coagulation; prostate; seminal vesicles; seminal plasma; rhesus monkey; human; evolution; nucleic acid sequence; cDNA; gene; semenogelin; b-microseminoprotein; Klinisk kemi; Proteins; enzymology; Proteiner; enzymologi;

    Sammanfattning : In man, the predominant proteins in the seminal plasma include semenogelin I, semenogelin II and b-microseminoprotein (MSP). Semenogelin I and II are both synthesized in the seminal vesicles and are the backbone of the gel formed upon semen coagulation. MSP is synthesized in the prostate, but its role has not yet been defined. LÄS MER

  3. 3. Pteridine dependent hydroxylases as autoantigens in autoimmune polyendocrine syndrome type 1

    Författare :Olov Ekwall; Uppsala universitet; []
    Nyckelord :Medical sciences; APS I; alopecia; autoantigen; cDNA; malabsorption; phenylalanine hydroxylase; pteridine; tryptophan hydroxylase; tyrosine hydroxylase; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Autoimmune polyendocrine syndrome type I (APS) is a monogenous, recessively inherited disease characterised by endocrine and non-endocrine autoimmune manifestations. One fifth of APS I patients suffer from periodic intestinal dysfunction with varying degrees of malabsorbtion, steatorrhea and constipation. LÄS MER

  4. 4. Genetic Profiling in Soft Tissue Sarcoma

    Författare :Princy Francis; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; synovial sarcoma; prognosis; Cytology; SS18-SSX; intratumor heterogeneity; aCGH; array comparative genomic hybridization; gene expression analysis; microarray; cDNA; Soft tissue sarcoma; cancerology; Cytologi; onkologi; cancer;

    Sammanfattning : Soft tissue sarcomas (STS) are a heterogeneous group of highly malignant mesenchymal tumors that account for ~1% of all malignancies. Frequent heterogeneity and pleomorphism along with suboptimal diagnostic reproducibility and insufficient prognostic markers make clinical management of these tumors difficult. LÄS MER

  5. 5. Radiosensitivity in lung cancer with focus on p53

    Författare :Michael Bergqvist; Claes Mercke; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Lung cancer; comet assay; p53; cDNA; p53 antibodies; Lungcancer; Komet metoden; p53 antikroppar; Onkologi; Oncology; Onkologi; Oncology; onkologi;

    Sammanfattning : In Sweden approximately 2800 new lung cancer patients are diagnosed every year. Radiotherapy is used with curative intention in certain groups of patients. The aim of this thesis is to study the basis of differences in radioresistance and the possibility to predict response to radiotherapy. LÄS MER