Sökning: "Malmö Klinisk kemi"

Visar resultat 1 - 5 av 43 avhandlingar innehållade orden Malmö Klinisk kemi.

1. 1. Development of a Method to Measure Plasma Levels of Activated Protein C in Complex with Protein C Inhibitor

   Författare :Karin Strandberg; Malmö Klinisk kemi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein C inhibitor; activated protein C; hypercoagulability; deep vein thrombosis; Clinical chemistry; myocardial infarction; Klinisk kemi;

   Sammanfattning : Acute myocardial infarction (MI) and deep venous thrombosis (DVT) are conditions caused by thrombus formation with activation of the coagulation system. The plasma concentration of the complex between activated protein C (APC) and protein C inhibitor (PCI), APC–PCI complex is increased in such states. LÄS MER

3. 2. Structural and functional studies of factor V in health and disease

   Författare :Mårten Steen; Malmö Klinisk kemi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; APC resistance and hemophilia; thrombosis; factor VIII; coagulation; factor V;

   Sammanfattning : The homologous blood coagulation factors V (FV) and factor VIII (FVIII) are important at sites of vascular injury for the amplification of the clotting cascade. Activated FV (FVa) serves as a cofactor to the enzyme activated factor X (FXa) in the activation of prothrombin. This complex is called the prothrombinase complex. LÄS MER

4. 3. Assessments of PSA Forms and hK2 as Very Early Predictors of Prostate Cancer

   Författare :David Ulmert; Malmö Klinisk kemi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate Cancer Screening; PSA; Prostate Cancer; Klinisk kemi; Clinical chemistry; Early Detection; hK2;

   Sammanfattning : Concentrations of prostate-specific antigen (PSA) and human kallikrein 2 (hK2) were investigated in blood samples that had been obtained from men who were diagnosed with prostate cancer (PCa) decades later. The studies were based on a cohort comprising 22,444 men who, in 1974?1986, were early middle aged and represented a non-PCa-screened population. LÄS MER

5. 4. Human glandular kallikrein 2 (hK2) in prostate cancer: Clinical and Methodological studies

   Författare :Charlotte Becker; Malmö Klinisk kemi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; screening; prostate cancer; PSA; Human glandular kallikrein; hK2; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

   Sammanfattning : Human glandular kallikrein 2 (hK2) is a predominantly prostate produced protein with many similarities to prostate-specific antigen (PSA). Just like for PSA elevated levels of hK2 can be found in men with protate cancer. We created an assay where hK2 in serum could reliably and with negligible cross-reactivity with PSA, be measured down to 0. LÄS MER

7. 5. Structure, evolution and expression of glandular kallikrein genes

   Författare :Yvonne Ceder; Malmö Klinisk kemi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ileum.; Clinical chemistry; Klinisk kemi; Tissue distribution; Androgen responsive element; Ortholog; Evolution; Prostate cancer; Glandular kallikreins; Prostate-specific antigen;

   Sammanfattning : Prostate-specific antigen (PSA) is a worldwide used tool for the diagnosis and monitoring of prostate cancer. It is a serine protease and belongs to the family of glandular kallikreins. Humans have three classical glandular kallikreins, but it has been reported that rodents have many more. LÄS MER