Sökning: "transglutaminase substrate"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden transglutaminase substrate.

  1. 1. Transglutaminase and peptidylarginine deiminase in the pathogenesis of autoimmune diseases

    Författare :Bodil Roth; Gastroenterologi; []
    Nyckelord :multiple sclerosis; pathogenesis; peptidylargininedeiminase; transglutaminase.; Sjögren’s syndrome; autoimmune; Alzheimer’s disease;

    Sammanfattning : Coeliac disease (CD) is becoming a model for understanding the pathogenesis of autoimmune disorders. In CD, antibodies against transglutaminase 2 (TG2) and specific glutamine residues of gliadins have been identified. LÄS MER

  3. 2. Proteomics of the Drosophila hemolymph clot and the function of transglutaminase

    Författare :Christine Wilhelmsson; Ulrich Theopold; Iréne Söderhäll; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; clotting; transglutaminase; innate immunity; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Sammanfattning : Insects rely on a fast and effective coagulation and wound response to avoid loss of body fluids and immobilize pathogens. Arthropod coagulation is in some respect equivalent to vertebrate coagulation but most factors and the regulation of coagulation systems seem not to be phylogenetically conserved. LÄS MER

  4. 3. Structure and organization of genes for the predominant seminal plasma proteins semenogelin I, semenogelin II and beta-microseminoprotein

    Författare :Magnus Ulvsbäck; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical chemistry; transglutaminase substrate; semen coagulation; prostate; seminal vesicles; seminal plasma; rhesus monkey; human; evolution; nucleic acid sequence; cDNA; gene; semenogelin; b-microseminoprotein; Klinisk kemi; Proteins; enzymology; Proteiner; enzymologi;

    Sammanfattning : In man, the predominant proteins in the seminal plasma include semenogelin I, semenogelin II and b-microseminoprotein (MSP). Semenogelin I and II are both synthesized in the seminal vesicles and are the backbone of the gel formed upon semen coagulation. MSP is synthesized in the prostate, but its role has not yet been defined. LÄS MER

  5. 4. Interactions Between Small Heat Shock Proteins and Substrate Proteins Mass Spectrometric Detection of Crosslinked Peptides to Map Protein-Protein Interactions

    Författare :Emma Åhrman; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Protein-protein interactions; Small heat shock proteins; Mass spectrometric peptide mapping; Proteins; enzymology; Proteiner; enzymologi;

    Sammanfattning : The small heat shock proteins (sHsps) are a widespread class of molecular chaperones existing in all organisms. During heat stress the sHsps protect other proteins from unfolding and aggregation. In plants the sHsps play an especially prominent part of the stress response. LÄS MER

  7. 5. Characterization and modelling of CEACAM1 interactions in cell signalling

    Författare :Kristmundur Sigmundsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : CEACAM1, the primordial carcino-embryonic Ag gene family member, is a transmembrane cell adhesion molecule expressed in leukocytes, epithelia, and blood vessel endothelia. As a result of differential splicing, CEACAM1 occurs as several isoforms, the two major ones being CEACAM1-L and -S, that have long (L) or short (S) cytoplasmic domains, respectively. LÄS MER