Sökning: "alopecia"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet alopecia.

1. 1. Alopecia and vitiligo in autoimmune polyendocrine syndrome type I

   Författare :Håkan Hedstrand; Uppsala universitet; []
   Nyckelord :Medical sciences; APS I; autoantigen; vitiligo; alopecia areata; cDNA-library; immunoscreening; tyrosine hydroxylase; SOX9; SOX10; molecular mimicry; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Sammanfattning : Autoimmune polyendocrine syndrome type I (APS I) is a recessively inherited disease caused by mutations in a recently identified gene, AIRE, on human chromosome 21. APS I patients are affected by autoimmune destruction of multiple endocrine glands and other organs as well as ectodermal structures. LÄS MER

3. 2. Pteridine dependent hydroxylases as autoantigens in autoimmune polyendocrine syndrome type 1

   Författare :Olov Ekwall; Uppsala universitet; []
   Nyckelord :Medical sciences; APS I; alopecia; autoantigen; cDNA; malabsorption; phenylalanine hydroxylase; pteridine; tryptophan hydroxylase; tyrosine hydroxylase; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Sammanfattning : Autoimmune polyendocrine syndrome type I (APS) is a monogenous, recessively inherited disease characterised by endocrine and non-endocrine autoimmune manifestations. One fifth of APS I patients suffer from periodic intestinal dysfunction with varying degrees of malabsorbtion, steatorrhea and constipation. LÄS MER

4. 3. Molecular Targets in Autoimmune Polyendocrine Syndrome Type1 and Their Clinical Implications

   Författare :Mohammad Alimohammadi; Olle Kämpe; Anna Lobell; Fredrik Rorsman; Tommy Olsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoimmunity; autoantibodies; endocrinology; parathyroid; hypoparathyroidism; Addison s disease; pulmonary symptoms; NALP; NALP5; NLR; KCNRG; Molecular medicine; Molekylär medicin;

   Sammanfattning : Autoimmune diseases occur when the immune system attacks and destroys healthy body tissue. Autoimmunity is known to cause a wide range of disorders, and is suspected to be responsible for many more. Most autoimmune disorders are chronic and cause severe morbidity for the patients, and are also costly for society. LÄS MER

5. 4. An exPADItion for citrullination in the developing hair follicle

   Författare :Kim Vikhe Patil; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : During epidermal development, to assure proper tissue structure, highly complex transcriptional networks interact within the stem cell compartments of the epidermis and hair follicles (HFs) to balance the choice between self-renewal or differentiation. The full characterisation of the protein profiles resulting from those transcriptional networks, within the compartments of the HF, remains, however, incomplete. LÄS MER

7. 5. Quality of life and severity assessment by provider and patient in oral and skin conditions

   Författare :Francesca Sampogna; Malmö högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : A good communication between patient and provider has the aimto understand the patient’s problems, to establish and maintain acaring relation, and to inform about disease. The quality of communicationmay have an influence on different important aspects, suchas satisfaction and adherence to treatment. LÄS MER