Sökning: "Virulence factor"

Visar resultat 6 - 10 av 156 avhandlingar innehållade orden Virulence factor.

1. 6. Haemophilus influenzae-induced acute otitis media. Aspects of virulence and protection in an animal model

   Författare :Åsa Melhus; Malmö Klinisk mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteriology; Microbiology; conjugate vaccine; protection; virulence; acute otitis media; Haemophilus influenzae; animal model; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Sammanfattning : Acute otitis media (AOM) is the most common illness diagnosed during early childhood. One of the major etiologic agents is Haemophilus influenzae. Apart from AOM, this organism can cause a broad range of infectious diseases such as meningitis, epiglottitis, arthritis, and pneumonia. Despite the importance of H. LÄS MER

3. 7. Virulence Factors and Motility Mechanisms of Pathogenic Neisseria

   Författare :Jens Eriksson; Ann-Beth Jonsson; Helena Aro; Tone Tønjum; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neisseria; Virulence factors; Type IV pili; PilT; PilU; NafA; NhhA; Twitching motility; molekylärgenetik; Molecular Genetics;

   Sammanfattning : Neisseria gonorrhoeae and Neisseria meningitidis are two closely related human specific pathogens. Neisseria gonorrhoeae is the causative agent for the sexually transmitted disease gonorrhea and often causes asymptomatic infections in women which is a cause of infertility. LÄS MER

4. 8. The Colonization Strategies of Nontypeable Haemophilus influenzae - Bacterial Colonization Factors and Vaccine Development

   Författare :Farshid Jalalvand; Malmö Klinisk mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ABC-transporter; bacterial colonization; Haemophilus influenzae; Haemophilus Protein F; laminin; NTHi; pathogenesis; vaccine; virulence; vitronectin.;

   Sammanfattning : Nontypeable Haemophilus influenzae (NTHi) is a remarkably proficient colonizer of the human respiratory tract. The aim of this thesis has been to characterize currently known, and identify novel, bacterial factors involved in the key processes of colonization and pathogenesis, namely adherence to host tissue and evasion of the host innate immunity. LÄS MER

5. 9. Roles of membrane vesicles in bacterial pathogenesis

   Författare :Svitlana Vdovikova; Sun Nyunt Wai; Richard Lundmark; Ann-Beth Jonsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane vesicles; autophagy; pore-forming toxin; pore formation; Listeria monocytogenes; Vibrio cholerae; virulence factor; PrtV protease; listeriolysin O; V. cholerae cytolysin; mikrobiologi; Microbiology; molekylärbiologi; Molecular Biology;

   Sammanfattning : The production of membranous vesicles is observed to occur among organisms from all domains of the tree of life spanning prokaryotes (bacteria, archaea) and eukaryotes (plants, animals and fungi). Bacterial release of membrane-derived vesicles (MVs) has been studied most extensively in cases of Gram-negative species and implicating their outer membrane in formation of extracellular MVs. LÄS MER

7. 10. Studies on secreted cysteine proteases of Streptococcus pyogenes : IdeS and SpeB

   Författare :Reine Vindebro; Ulrich von Pawel-Rammingen; Wolfgang Knecht; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Streptococcus pyogenes; Group A Streptococci; GAS; virulence factor; IdeS; SpeB; cysteine protease; protease inhibitor; IgG; immune evasion; molekylär bioteknik inst f molekylärbiologi ; molecular biotechnology dept of molecular biology ;

   Sammanfattning : The pathogen Streptococcus pyogenes is a significant cause of human morbidity and mortality. Most of the work in this thesis is focused on streptococcal virulence factor IdeS, but the thesis also features work on SpeB, another streptococcal virulence factor. LÄS MER