Sökning: "Listeria monocytogenes"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden Listeria monocytogenes.

  1. 1. New alternatives to combat Listeria monocytogenes and Chlamydia trachomatis Design, synthesis, and evaluation of substituted ring-fused 2-pyridones as anti-virulent agents

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Martina Kulén; Umeå universitet.; [2018]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antibiotic resistance; anti-virulence; Listeria monocytogenes; Chlamydia trachomatis; ring-fused 2-pyridone; organic synthesis; structure-based design; PrfA; drug design; structure-activity relationship;

    Sammanfattning : Antibiotic resistance has become a global health burden with the number of resistant bacteria continuously increasing. Antibiotic drugs act by being either bactericidal (killing bacteria) or bacteriostatic (inhibiting growth of bacteria). However, these modes of action increase the selective pressure on the bacteria. LÄS MER

  3. 2. Regulatory pathways and virulence inhibition in Listeria monocytogenes

    Detta är en avhandling från Umeå : Umeå Universitet

    Författare :Christopher Andersson; Umeå universitet.; Umeå universitet.; Umeå universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Listeria monocytogenes; PrfA; ActA; infection; molekylärbiologi; Molecular Biology;

    Sammanfattning : Listeria monocytogenes is a rod-shaped Gram positive bacterium. It generally exist ubiquitously in nature, where it lives as a saprophyte. Occasionally it however enters the food chain, from where it can be ingested by humans and cause gastro-intestinal distress. In immunocompetent individuals L. LÄS MER

  4. 3. RNA-mediated virulence gene regulation in the human pathogen Listeria monocytogenes

    Detta är en avhandling från Umeå, Sweden : Print & Media

    Författare :Edmund Loh; Umeå universitet.; Umeå universitet.; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Listeria monocytogenes; virulence; ncRNAs; PrfA; 5´-UTRs; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The Gram-positive human pathogen Listeria monocytogenes uses a wide range of virulence factors for its pathogenesis. The majority of its virulence genes are encoded on a 9-kb pathogenicity island and are controlled by the transcriptional activator PrfA. LÄS MER

  5. 4. Regulatory roles of two small RNAs in the human pathogen Listeria monocytogenes and the evaluation of an alternative infection model

    Detta är en avhandling från Umeå : Umeå Universitet

    Författare :Jonas Gripenland; Umeå universitet.; Umeå universitet.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small RNA; sRNA; Riboswitch; Listeria monocytogenes; ncRNA; PrfA; molekylärbiologi; Molecular Biology;

    Sammanfattning : Listeriosis is a potentially lethal disease caused by the Gram-positive facultative intracellular pathogen Listeria monocytogenes (L.m.). L. LÄS MER

  7. 5. Stress induced virulence of Staphylococcus aureus and Listeria monocytogenes

    Detta är en avhandling från Faculty of Engineering, Lund University

    Författare :Nikoleta Zeaki; Lund University.; Lunds universitet.; [2015]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Control of the dissemination of pathogens in the food production chain is an on-going process with new challenges emerging as pathogenic bacteria evolve and express enhanced virulence characteristics. Staphylococcus aureus and Listeria monocytogenes are two notorious pathogens responsible for staphylococcal food poisoning (SFP) and listeriosis: a foodborne intoxication and an infectious disease respectively. LÄS MER