Sökning: "V. cholerae cytolysin"
Visar resultat 1 - 5 av 6 avhandlingar innehållade orden V. cholerae cytolysin.
1. Roles of membrane vesicles in bacterial pathogenesis
Sammanfattning : The production of membranous vesicles is observed to occur among organisms from all domains of the tree of life spanning prokaryotes (bacteria, archaea) and eukaryotes (plants, animals and fungi). Bacterial release of membrane-derived vesicles (MVs) has been studied most extensively in cases of Gram-negative species and implicating their outer membrane in formation of extracellular MVs. LÄS MER
2. Vibrio cholerae modulates the immune defense of human gut mucosa
Sammanfattning : The key function of innate immunity is to sense danger signals and initiate effective responses as a defense mechanism against pathogens. Simultaneously, effector responses must be regulated to avoid excessive inflammation with resulting tissue damage. LÄS MER
3. Roles of secreted bacterial factors in modulation of host cell signalling
Sammanfattning : Pathogenic bacteria employ several secretion systems to release or inject virulence factors that may alter host cell processes, generate a replicative niche, and aid bacterial survival in adverse environments. This thesis presents my investigations on how bacterial factors can modulate host cell signalling mechanisms. LÄS MER
4. Effects of Vibrio cholerae protease and pigment production on environmental survival and host interaction
Sammanfattning : Only two out of more than 200 V. cholerae serogroups, classified on the basis of LPS structure, are associated with epidemic or pandemic cholera. These toxigenic serogroups carry phage-derived pathogenicity islands coding for the main virulence factors for establishment of cholera disease – cholera toxin (CTX) and toxin-coregulated pilus (TCP). LÄS MER
5. Studies of pore-forming bacterial protein toxins in Escherichia coli
Sammanfattning : Escherichia coli, a Gram-negative bacterium, which can be classified into three groups: the commensal, intestinal pathogenic (IPEC) and extra-intestinal pathogenic (ExPEC) E. coli. The cytolysin A (ClyA) protein, a 34-kDa pore-forming toxin, encoded by a gene found in both non-pathogenic and pathogenic E. LÄS MER