Sökning: "multiple hypothesis test"

Visar resultat 1 - 5 av 52 avhandlingar innehållade orden multiple hypothesis test.

  1. 1. Model-Based Hypothesis Testing in Biomedicine : How Systems Biology Can Drive the Growth of Scientific Knowledge

    Författare :Rikard Johansson; Gunnar Cedersund; Tomas Strömberg; Peter Strålfors; Marija Cvijovic; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; systems biology; modeling; ODE; hypothesis testing; falsificationism; insulin signaling; yeast; population heterogeneity; cell-to-cell variation; facilitation; pyramidal; synaptic; bootstrapping; personalized medicine; omics;

    Sammanfattning : The utilization of mathematical tools within biology and medicine has traditionally been less widespread compared to other hard sciences, such as physics and chemistry. However, an increased need for tools such as data processing, bioinformatics, statistics, and mathematical modeling, have emerged due to advancements during the last decades. LÄS MER

  3. 2. Identifying Influential Observations in Nonlinear Regression : a focus on parameter estimates and the score test

    Författare :Karin Stål; Tatjana von Rosen; Sune Karlsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Added parameter plot; differentiation approach; influential observation; nonlinear regression; score test; Statistics; statistik;

    Sammanfattning : This thesis contributes to influence analysis in nonlinear regression and in particular the detection of influential observations. The focus is on a regression model with a known mean function, which is nonlinear in its parameters and where the function is chosen according to the knowledge about the process generating the data. LÄS MER

  4. 3. Proteomics and metabolomics in biological and medical applications

    Författare :Liudmila Shiryaeva; Wolfgang P. Schröder; Pernilla Wikström; Peter Roepstroff; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; 2D-DIGE; biomarkers; cold-acclimation; conifer; freezing tolerance; GC-MS; metabolomics; multiple hypothesis test; multivariate analysis; OPLS-DA; Picea obovata; plasma; prostate cancer; proteomics; ProteoMiner; Siberian spruce;

    Sammanfattning : Biological processes in living organisms consist of a vast number of different molecular networks and interactions, which are complex and often hidden from our understanding. This work is focused on recovery of such details for two quite distant examples: acclimation to extreme freezing tolerance in Siberian spruce (Picea obovata) and detection of proteins associated with prostate cancer. LÄS MER

  5. 4. On Detection and Estimation of Multiple Sources in Radar Array Processing

    Författare :Jonny Eriksson; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; spatially correlated noise; Cramer-Rao bounds; estimation; feature reduction; virtual uniform linear arrays; classification; adaptive data reduction; nonlinear weighted least squares; multiple targets; detection;

    Sammanfattning : This thesis deals with detection and estimation problems in sensor array signal processing. We treat the multiple hypothesis problem for complex sinusoids observed in spatially colored noise. LÄS MER

  7. 5. Essays on Panel Cointegration

    Författare :Joakim Westerlund; Nationalekonomiska institutionen; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Nationalekonomi; ekonometri; ekonomisk teori; ekonomiska system; ekonomisk politik; Cross-Sectional Dependence; Common factor restriction; Feldstein-Horioka Puzzle; Fisher Hypothesis; economic policy; economic theory; economic systems; Economics; econometrics; Structural Break.; Sieve Bootstrap; Information Criteria; Residual-Based Cointegration Test; Panel Cointegration; Monte Carlo Simulation; Model Selection; International R D Spillovers; International Health Care Expenditures;

    Sammanfattning : This thesis develops new techniques for analyzing cointegrated relationships in panel data. The first chapter is introductory while the remaining six contain the main contributions. LÄS MER