Sökning: "conjugate vaccine"

Visar resultat 1 - 5 av 17 avhandlingar innehållade orden conjugate vaccine.

  1. 1. Infectious and bleeding complications in patients with hematological malignancies Studies on diagnosis and prevention

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Tobias Svensson; Uppsala universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic lymphocytic leukemia; Immunodeficiency; Hypogammaglobulinemia; IgG subclass; Pneumococci; Pneumococcal vaccine; Polysaccharide vaccine; Protein-conjugate vaccine; Aspergillosis; Bronchoalveolar lavage; Invasive fungal disease; Pneumocystis jirovecii pneumonia; Myelodysplastic syndrome; Azacitidine; Eltrombopag; Thrombocytopenia; Thrombopoietin receptor; Oncology; Onkologi;

    Sammanfattning : The overall aim of this thesis is to improve knowledge about the prevention of infectious and bleeding complications in patients with hematological malignancies, primarily in those with chronic lymphocytic leukemia (CLL) and myelodysplatic syndrome (MDS).Hypogammaglobulinemia, impaired production of immunoglobulins (Ig), is an established risk factor for infection, but the impact of IgG pure subclass deficiency (IgG subclass deficiency with adequate production of IgG, IgA, and IgM) has been debated. LÄS MER

  2. 2. Impact of the inflammatory response on specific immunity in neurosurgical patients

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Anna Ljunghill Hedberg; Uppsala universitet.; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; T-cell-dependent vaccine; T-cell-independent vaccine; CNS injury-induced immune deficiency syndrome; pneumococcal conjugate vaccine; pneumococcal polysaccharide vaccine; posttraumatic meningitis.; Medicinsk vetenskap; Medical Science; Infektionssjukdomar; Infectious Diseases;

    Sammanfattning : Vaccination with a T-cell-dependent pneumococcal conjugate vaccine (PCV) followed by a T-cell-independent pneumococcal polysaccharide vaccine (PPSV) is recommended after basilar skull fracture to reduce the risk of meningitis. The optimal time frame for vaccination has not yet been established and varies widely in practice. LÄS MER

  3. 3. Antibody- and Peptide-based Immunotherapies Proof-of-concept and safety considerations

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Erika Fletcher; Uppsala universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immune complex; conjugat; vaccine; CD40; whole blood; cytokine release syndrome; Immunologi; Immunology;

    Sammanfattning : The aim of cancer immunotherapy is to eradicate tumours by inducing a tumour-specific immune response. This thesis focuses on how antibodies and peptides can improve antigen presentation and the subsequent tumour-specific T cell response. Tumour recognition by the immune system can be promoted through delivery of antigen in the form of a vaccine. LÄS MER

  4. 4. Immunogenicity and protective potential of Protein D of Haemophilus influenzae against H. influenzae infection

    Detta är en avhandling från Medical Microbiology, Lund University

    Författare :Mustafa Akkoyunlu; Lund University.; Lunds universitet.; [1997]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; bactericidal assay; mucosal immunity; otitis media; vaccine; H. influenzae; protein D; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Both Haemophilus influenzae type b (Hib) and nontypeable H. influenzae (NTHi) are important human pathogens causing invasive and mucosal infections. Currently there are number of vaccines available against Hib infections. LÄS MER

  5. 5. Haemophilus influenzae-induced acute otitis media. Aspects of virulence and protection in an animal model

    Detta är en avhandling från Divison of Medical Microbiology

    Författare :Åsa Melhus; Lund University.; Lunds universitet.; [1997]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteriology; Microbiology; conjugate vaccine; protection; virulence; acute otitis media; Haemophilus influenzae; animal model; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Acute otitis media (AOM) is the most common illness diagnosed during early childhood. One of the major etiologic agents is Haemophilus influenzae. Apart from AOM, this organism can cause a broad range of infectious diseases such as meningitis, epiglottitis, arthritis, and pneumonia. Despite the importance of H. LÄS MER