Sökning: "Helena Aro"

Hittade 4 avhandlingar innehållade orden Helena Aro.

  1. 1. Virulence Factors and Motility Mechanisms of Pathogenic Neisseria

    Författare :Jens Eriksson; Ann-Beth Jonsson; Helena Aro; Tone Tønjum; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neisseria; Virulence factors; Type IV pili; PilT; PilU; NafA; NhhA; Twitching motility; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Neisseria gonorrhoeae and Neisseria meningitidis are two closely related human specific pathogens. Neisseria gonorrhoeae is the causative agent for the sexually transmitted disease gonorrhea and often causes asymptomatic infections in women which is a cause of infertility. LÄS MER

  3. 2. Pathogenic Neisseria infections of human neutrophils and epithelial cells : focusing on host responses and immune evasion

    Författare :Niklas Söderholm; Helena Aro; Thomas Rudel; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neisseria meningitidis; Neisseria gonorrhoeae; Neutrophils; PMN; Epithelial cells; Polarized cells; Type IV pili; Adherence; Cell cycle; DNA damage; Lactobacillus; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : N. meningitidis and N. gonorrhoeae are obligate human pathogens that colonize mucosal surfaces and are often carried asymptomatically. These bacteria have developed adhesive structures that promote adherence to host cells and efficient colonization of new hosts. LÄS MER

  4. 3. Neisseria gonorrhoeae and Lactobacillus from initial adherence to effects on human cells

    Författare :Katarina Vielfort; Helena Aro; Bernt Eric Uhlin; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neisseria gonorrhoeae; Lactobacillus; adhesion; cell cycle; DNA damage; Neutrophils; molekylärgenetik; Molecular Genetics;

    Sammanfattning : The causative agent of gonorrhoea Neisseria gonorrhoeae (gonococcus) colonises the urogenital tract epithelia. The vaginal tract microbiota of healthy females is dominated by Lactobacillus species. In paper I, the ability of lactobacilli to protect cervical cells against gonococcal adherence was investigated. LÄS MER

  5. 4. Host epithelium integrity in the female reproductive tract during Neisseria gonorrhoeae infection

    Författare :Linda Weyler; Helena Aro; Lene Rasmussen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Female reproductive tract; Neisseria gonorrhoeae; VK2 E6E7 cells; DNA damage; cell cycle; mitosis; restriction endonucleases; infection models; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Neisseria gonorrhoeae infections are asymptomatic in approximately fifty percent of the affected women. Left untreated, this can develop into a long-term inflammatory state with detrimental secondary complications such as ectopic pregnancy and sterility. Furthermore, studies have shown that N. LÄS MER