Sökning: "Serine protease"

Visar resultat 11 - 15 av 108 avhandlingar innehållade orden Serine protease.

  1. 11. Intermediate State Stabilisation in Enzyme Catalysis Structural studies of two serine proteases and a photosynthetic reaction centre

    Författare :Gergely Katona; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; photosynthetic reaction centre; X-ray crystallography; structural mechanism; enzyme kinetics; serine protease; enzyme intermediate; enzyme catalysis;

    Sammanfattning : Enzymes play a key role in every organisms life. They catalyse chemical reactions and may also respond to external stimulus. The reoccurring theme of this thesis is how biologically relevant information can be gleaned from X-ray structures of the enzymes. LÄS MER

  3. 12. The Structural Modularity and Inherent Dynamics of the DegP Protease together with its Intertwined Role in the Bacterial Periplasm

    Författare :Darios Šulskis; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; serine protease; DegP; nuclear magnetic resonance; E. coli; protein quality control; chaperone; HtrA;

    Sammanfattning : The protein quality control machinery is a delicate and integrated network of molecular tools working together to fold or remove unwanted proteins from the cell. A distinct set of “gatekeepers” are involved in this process including molecular chaperones, proteases, oxidoreductases, transferases, and many others in both eukaryotic and prokaryotic organisms. LÄS MER

  4. 13. Serine protease inhibitors in the upper and lower airways

    Författare :Camilla Hollander; Enheten för kroniska inflammatoriska och degenerativa sjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; auditive system and speech; Neutrophils; audiology; Otorhinolaryngology; Medicin människa och djur ; AAT; Medicine human and vertebrates ; SLPI; cytokines chemokines; anti-proteases; audiologi; hörsel- och talorganen; Airway inflammation; Otorinolaryngologi;

    Sammanfattning : Proteases and their inhibitors are implicated in the physiology and pathology of the airways. Protease inhibitors include those produced locally, such as secretory leukocyte protease inhibitor (SLPI), and those produced mainly by the liver that can reach the airways via passive diffusion, such as alpha1-antitrypsin (AAT). LÄS MER

  5. 14. Deg/HtrA proteases of the cyanobacterium Synechocystis sp. PCC 6803 : from biochemical characterization to their physiological functions

    Författare :Xuân Tâm Lâm; Christiane Funk; Jörg Nickelsen; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Deg; HtrA; protease; chaperone; Synechocystis sp. PCC 6903; biochemical characterization; physiological function; proteomics; structure;

    Sammanfattning : The family of Deg/HtrA proteases is present in a wide range of organisms from bacteria, archaea to eukaryota. These ATP-independent serine endopeptidases play key roles in the cellular protein quality control. The cyanobacterium Synechocystis sp. LÄS MER

  7. 15. Enhanced Enzymatic Hydrolysis of Lignocellulose in Bioethanol Production Substrate Interactions with Surfactants and Polymers

    Författare :Johan Börjesson; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; enzymologi; Penicillium brasilianum; SSF; Ethanol; Proteins; enzymology; Proteiner; Protease; Adsorption; PEG; Surfactant; Hydrolysis; Lignocellulose; Cellulase; Hypocrea jecorina; Trichoderma reesei; Cellulose;

    Sammanfattning : Ethanol produced from cellulose is a promising future alternative fuel. The production process has three main steps: (i) pretreatment of raw material to increase degradability; (ii) enzymatic hydrolysis of cellulose to produce glucose; (iii) fermentation of glucose into bioethanol. LÄS MER