Sökning: "AAT"

Visar resultat 1 - 5 av 44 avhandlingar innehållade ordet AAT.

  1. 1. Chronic Obstructive Pulmonary Disease: Role of Alpha-1-antitrypsin

    Författare :Ruta Aldonyte; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Andningsorganen; Respiratory system; monocytes; inflammation; AAT polymerization; AAT; COPD;

    Sammanfattning : The only proven genetic risk factor for Chronic Obstructive Pulmonary Disease (COPD) is an inherited Z (Glu342¡úLys) deficiency of alpha-1-antitrypsin (AAT), a major inhibitor of neutrophil elastase. In vivo, AAT is found in both native (inhibitory) and modified (non-inhibitory) forms. LÄS MER

  3. 2. Serine protease inhibitors in the upper and lower airways

    Författare :Camilla Hollander; Enheten för kroniska inflammatoriska och degenerativa sjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; auditive system and speech; Neutrophils; audiology; Otorhinolaryngology; Medicin människa och djur ; AAT; Medicine human and vertebrates ; SLPI; cytokines chemokines; anti-proteases; audiologi; hörsel- och talorganen; Airway inflammation; Otorinolaryngologi;

    Sammanfattning : Proteases and their inhibitors are implicated in the physiology and pathology of the airways. Protease inhibitors include those produced locally, such as secretory leukocyte protease inhibitor (SLPI), and those produced mainly by the liver that can reach the airways via passive diffusion, such as alpha1-antitrypsin (AAT). LÄS MER

  4. 3. Beta Cell Function: from Human Genetics to Animal Models

    Författare :Martins Kalis; Diabetes - immunovirologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; animal model; Dicer1; genetics; genetic association; single nucleotide polymorphism; SNP; INS-1E; AAT; FOXP3; beta cell function; insulin secretion; FFAR1; insulin; T2D; glucose; T1D;

    Sammanfattning : Beta cell function is an important factor in the development of both Type 1 (T1D) and Type 2 (T2D) diabetes mellitus. T1D is characterized by a primary defect in insulin secretion due to the immune-mediated beta cell destruction, however, the more common T2D beside insulin resistance also include impaired beta cell function as a consequence to abnormal glucose homeostasis. LÄS MER

  5. 4. Activation of human B cells with the Moraxella catarrhalis IgD-binding protein MID

    Författare :Radinka Hadzic; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mikrobiologi; bakteriologi; virology; mycology; bacteriology; AAT; Microbiology; tonsils; CD19; CD21; MID; B cells; serology; virologi; mykologi; Immunology; transplantation; Immunologi; serologi; Moraxella catarrhalis;

    Sammanfattning : Moraxella catarrhalis is a respiratory tract pathogen that causes significant health problems, including acute otitis media in children, lower respiratory tract infections in adults and the elderly and sinusitis in both children and adults. The interest in M. LÄS MER

  7. 5. Characterization and design of printed RFID solutions

    Författare :Johan Sidén; Mittuniversitetet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; RFID; Printed Antennas; AAT; Electrical engineering; electronics and photonics; Elektroteknik; elektronik och fotonik;

    Sammanfattning : .... LÄS MER