Sökning: "HtrA"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet HtrA.

  1. 1. Deg/HtrA proteases of the cyanobacterium Synechocystis sp. PCC 6803 : from biochemical characterization to their physiological functions

    Författare :Xuân Tâm Lâm; Christiane Funk; Jörg Nickelsen; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Deg; HtrA; protease; chaperone; Synechocystis sp. PCC 6903; biochemical characterization; physiological function; proteomics; structure;

    Sammanfattning : The family of Deg/HtrA proteases is present in a wide range of organisms from bacteria, archaea to eukaryota. These ATP-independent serine endopeptidases play key roles in the cellular protein quality control. The cyanobacterium Synechocystis sp. LÄS MER

  3. 2. The Structural Modularity and Inherent Dynamics of the DegP Protease together with its Intertwined Role in the Bacterial Periplasm

    Författare :Darios Šulskis; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; serine protease; DegP; nuclear magnetic resonance; E. coli; protein quality control; chaperone; HtrA;

    Sammanfattning : The protein quality control machinery is a delicate and integrated network of molecular tools working together to fold or remove unwanted proteins from the cell. A distinct set of “gatekeepers” are involved in this process including molecular chaperones, proteases, oxidoreductases, transferases, and many others in both eukaryotic and prokaryotic organisms. LÄS MER

  4. 3. Stress response in the cyanobacterium Synechocystis sp. PCC 6803

    Författare :Helder Miranda; Christiane Funk; Hans-Erik Åkerlund; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cyanobacteria; High light; heat stress; ROS; Photosynthesis; Photosystem II; Deg HtrA proteases; small CAB-like proteins; Refraction-2D™; MALDI-TOF; 2D-gel; GC-MS; PCA; OPLS-DA; EPS; S-layer; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Adaptation to environmental changes is important for the survival of living organisms. Under extreme abiotic conditions, organic molecules (such as lipids, proteins and nucleic acids) are prone to damage. LÄS MER

  5. 4. Glycan-based interactions of Streptococcus pneumoniae and the host

    Författare :Karina Hentrich; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Streptococcus pneumoniae is commonly found as an asymptomatic colonizer of the nasopharynx of children, but it can also translocate to normally sterile body sites and cause severe diseases, like pneumonia, septicemia or meningitis. Pneumococci spread via aerosols. LÄS MER

  7. 5. Functional details of human HtrA2 protease studied by NMR spectroscopy

    Författare :Emelie E. Aspholm; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; HtrA2; nuclear magnetic resonance; protein quality control; neurodegenerative disease; apoptosis;

    Sammanfattning : Cells rely on an array of cellular machineries in the protein quality control system (PQC) to maintain the health of the collective proteome. The HtrA family of serine proteases are found in all kingdoms of life and function in the PQC by degrading damaged and aggregated proteins as well as by acting as molecular chaperones. LÄS MER