Sökning: "SH-SY5Y"

Visar resultat 11 - 15 av 55 avhandlingar innehållade ordet SH-SY5Y.

  1. 11. Effects of ellagic acid in human neuroblastoma cells

    Författare :Christina Fjæraa Alfredsson; Eewa Nånberg; Karin Persson; Karlstads universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; polyphenols; ellagic acid; neuroblastoma; SH-SY5Y cells; differentiation; proliferation; apoptosis; cell adhesion; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : A diet rich in polyphenols has been proposed to have beneficial health effects and to reduce risk of disease. Ellagic acid, a polyphenol common in red berries and pomegranates, has potential anti-tumorigenic effects that make it interesting to further study in different cancer cell systems. LÄS MER

  3. 12. Effects of ethanol on the expression of immediate-early genes in nerve cells

    Författare :Wei-Qun Ding; Institutionen för laboratoriemedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroadaptation; the central nervous system; AP-1; junD; junB; c-jun; fosB; c-fos; neuroblastoma SH-SY5Y; ethanol; immediate-early genes; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : Immediate-early genes of the fos and jun families encode proteins that dimerize to form a complex of activator protein 1 and regulate the expression of a number of genes in the nervous system. Ethanol has previously been shown to induce alterations in expression of fos and jun genes in the brain. LÄS MER

  4. 13. Expression and localisation of somatostatin receptor subtype 2a in neuroendocrine cells and cells of neuroectodermal origin

    Författare :Sayed Hossein Hashemi; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SSR2 a receptor; somatostatin; neuroendocrine tumours; tissue culture; immunocytochemistry; ; SH-SY5Y cells; CAD cell line; ependyma; tanycytes; neuronal differentiation; catecholaminergic markers; ; cholinergic markers; synaptic vesicle membrane proteins; intermediate filaments.;

    Sammanfattning : .... LÄS MER

  5. 14. Cell interactions in the CNS and their consequences for neuronal apoptosis

    Författare :Mikaela Berglund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Aggregate cultures; apoptosis; automated image analysis; cytochrome c; interactions; JNK; microglia; neuron; neural precursor cells; rotenone; UV.;

    Sammanfattning : The central nervous system consists of an intricate network of neurons and glial cells that depend on reciprocal communication to develop and maintain the vital functions of the brain. if the balance is disturbed by injury or disease, two cell types in particular, microglia and astrocytes, respond by producing factors that help combat the infection or delimit the affected area. LÄS MER

  7. 15. In vitro modelling of tau phosphorylating kinases : emphasis of Cdk5

    Författare :Anne Jämsä; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The main hallmarks of Alzheimer’s disease (AD) are extracellular deposits of betaamyloid (Aβ) and intracellular neurofibrillary tangles (NFT) composed of highly phosphorylated tau protein. Abnormal hyperphosphorylation of tau is the most deleterious step in NFT formation making the use of kinase inhibitors an attractive treatment possibility in AD. LÄS MER