Sökning: "Anne Jämsä"

Hittade 1 avhandling innehållade orden Anne Jämsä.

1. 1. In vitro modelling of tau phosphorylating kinases : emphasis of Cdk5

   Författare :Anne Jämsä; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The main hallmarks of Alzheimer’s disease (AD) are extracellular deposits of betaamyloid (Aβ) and intracellular neurofibrillary tangles (NFT) composed of highly phosphorylated tau protein. Abnormal hyperphosphorylation of tau is the most deleterious step in NFT formation making the use of kinase inhibitors an attractive treatment possibility in AD. LÄS MER