Sökning: "neuroadaptation"

Hittade 2 avhandlingar innehållade ordet neuroadaptation.

  1. 1. Effects of ethanol on the expression of immediate-early genes in nerve cells

    Författare :Wei-Qun Ding; Institutionen för laboratoriemedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroadaptation; the central nervous system; AP-1; junD; junB; c-jun; fosB; c-fos; neuroblastoma SH-SY5Y; ethanol; immediate-early genes; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : Immediate-early genes of the fos and jun families encode proteins that dimerize to form a complex of activator protein 1 and regulate the expression of a number of genes in the nervous system. Ethanol has previously been shown to induce alterations in expression of fos and jun genes in the brain. LÄS MER

  2. 2. Gene expression profiling in animal models of alcoholism

    Författare :Christina Arlinde; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Alcoholism; gene expression; microarray; animal model; rat; brain;

    Sammanfattning : Genetic and environmental factors in alcoholism interact at the level of the transcriptome to encode the phenotypic traits of this complex clinical syndrome. Because of this, the prospect of simultaneous, genome wide, high-throughput analysis of gene expression in key brain areas potentially offers a novel strategy to identify new molecular treatment targets in this disease. LÄS MER