Sökning: "junB"
Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet junB.
1. Effects of ethanol on the expression of immediate-early genes in nerve cells
Sammanfattning : Immediate-early genes of the fos and jun families encode proteins that dimerize to form a complex of activator protein 1 and regulate the expression of a number of genes in the nervous system. Ethanol has previously been shown to induce alterations in expression of fos and jun genes in the brain. LÄS MER
2. Behavioural and biochemical pharmacology of adenosine/dopamine receptor/receptor interaction
Sammanfattning : The neurotransmitter dopamine seems to be involved in neuropsychiatric diseases such as schizophrenia and Parkinson's disease. Direct blockade of dopamine receptors of the D2 subtype has been the hallmark of pharmacotherapy for schizophrenia since early 1950s. LÄS MER
3. Alcohol and gene expression in nerve cells with emphasis on transcription factor AP-1
Sammanfattning : Alcohol induces profound effects on the function of the nerve cells in the nervous system. Alterations in gene expression is an important way by which these effects could be induced and sustained. Activating Protein-1 (AP-1) is a dimeric transcription factor constituted of proteins from the fos and jun immediate-early gene families. LÄS MER
4. Molecular Characterization of Experimental Traumatic Brain Injury
Sammanfattning : Traumatic brain injury (TBI) is the most common cause of mortality and disability in the younger (.... LÄS MER
5. Mechanisms of type I interferons in autoimmunity and cancer
Sammanfattning : Interferons (IFNs) were first described in the 1950’s and has since been characterized as potent inducers of pathogen defense mechanisms. Since then, researchers have uncovered a depth of mechanisms in the IFN system extending beyond immune modulation of pathogen defense. LÄS MER