Sökning: "Institutionen för laboratoriemedicin"

Visar resultat 1 - 5 av 474 avhandlingar innehållade orden Institutionen för laboratoriemedicin.

  1. 1. The clinical value of genetic analyses of bone and soft tissue tumors

    Författare :Charles Walther; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Tumors of bone and soft tissue are common but only constitute 1 % of all malignant tumors. The malignant tumors are often difficult to diagnose due to their rarity and morphological resemblance between subtypes. This makes the diagnostic process challenging. LÄS MER

  3. 2. Molecular Genetic Characterization of Acute Lymphoblastic Leukemia with a Poor Prognosis

    Författare :Setareh Safavi; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute lymphoblastic leukemia; hypodiploidy; adult acute lymphoblastic leukemia;

    Sammanfattning : Acute lymphoblastic leukemia (ALL) affects individuals at all ages, with peak incidences in children 50 years. ALL is broadly categorized into B-cell precursor (BCP) and T-cell ALL with specific clinical features associated with outcome. LÄS MER

  4. 3. Human Bone Marrow Microenvironment in Health and Disease

    Författare :Sandro Bräunig; Avdelningen för molekylär hematologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoietic microenvironment; Imaging; Myeloproliferative neoplasms; Spatial relationships; acute lymphoblastic leukaemia ALL ; Fibrosis; Mesenchymal stromal cell; Single cell RNA sequencing;

    Sammanfattning : Hematopoietic stem cells (HSCs) are safeguarded from various threats such as stress, injury, or radiationwithin specialized microenvironments or niches within the bone marrow. In this thesis, we investigatedvarious facets of the bone marrow (BM) microenvironment and its critical role in hematopoiesis andrelated disorders. LÄS MER

  5. 4. Molecular Markers and Hypoxia in Renal Cell Carcinoma

    Författare :Roger de Alwis; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney cancer; CTC; RCC; Hypoxia; SEMA5B; Prognostic markers;

    Sammanfattning : Renal cell carcinomas (RCCs) are a group of tumours that arise from the nephron within the kidney. They are characterised by an indolent growth pattern and do not display overt clinical symptoms in patients with early to locally advanced tumours. LÄS MER

  7. 5. Autoimmune disease – phenotypic alterations of peripheral immune cells and clinical correlates

    Författare :Evelina Elmér; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ANCA-associated vasculitis; immunization; relapse; rheumatoid arthritis; sequence variant;

    Sammanfattning : .... LÄS MER