Sökning: "catecholaminergic markers"

Hittade 5 avhandlingar innehållade orden catecholaminergic markers.

  1. 1. Expression and localisation of somatostatin receptor subtype 2a in neuroendocrine cells and cells of neuroectodermal origin

    Författare :Sayed Hossein Hashemi; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SSR2 a receptor; somatostatin; neuroendocrine tumours; tissue culture; immunocytochemistry; ; SH-SY5Y cells; CAD cell line; ependyma; tanycytes; neuronal differentiation; catecholaminergic markers; ; cholinergic markers; synaptic vesicle membrane proteins; intermediate filaments.;

    Sammanfattning : .... LÄS MER

  3. 2. Attention-deficit/hyperactivity disorder : alterations of motor behaviour and dopaminergic transmission

    Författare :Aurelija Jucaite; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :AD HD; DCD; neurodevelopmental disorder; PET; dopamine transporter; dopamine D2 receptors; raclopride; striatum; midbrain; anticipatory postural adjustments;

    Sammanfattning : Altered catecholaminergic neurotransmission in the brain has long been thought to be of importance in the regulation of motor behavior and cognitive performance in children who had symptoms of distractability, impulsivity and clumsiness. The dopamine theory of AD/HD has mainly been substantiated by: i) the effects of psychostimulants, which target the dopamine transporter (DAT), and thereby reduce impulsiveness and inattentiveness, increase the striatal cerebral blood flow and functional activity, and ii) the evidence from linkage studies associating the AD/HD syndrome with allelic variations of genes encoding the dopamine transporter and, possibly, the dopamine D4 receptors. LÄS MER

  4. 3. LIFE EVENTS, STRESS AND COPING

    Författare :Charlotta Sunnqvist; Lund Psykiatri; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coping strategies; biological stressmarkers; SUAS-S; Suicide attempt; time-geographic life charting;

    Sammanfattning : In order to increase the understanding of suicidal behaviour, the general aim of the thesis is to gain a profound knowledge of the suicidal individual, and hence to find and ensure a preventive strategy. This will be accomplished by finding and trying new methods for evaluation of suicide risk. LÄS MER

  5. 4. Innervation patterns and locally produced signal substances in the human patellar tendon : of importance when understanding the processes of tendinosis

    Författare :Patrik Danielson; Sture Forsgren; Håkan Alfredson; Graham Riley; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; patellar tendon; innervation; tendinosis; tendinopathy; acetylcholine; catecholamines; muscarinic receptors; adrenergic receptors; Anatomy; Anatomi;

    Sammanfattning : Tendinosis is a condition of chronic pain that afflicts several human tendons, not least the patellar tendon, in which case it is often clinically referred to as ‘jumper’s knee’. The exact mechanisms behind tendinosis are yet not fully understood. LÄS MER

  7. 5. The non-human primate as a model of human parkinsonism

    Författare :Alison McCormack; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Parkinson s disease; substantia nigra; aging; neuromelanin; MPTP; alpha-synuclein; levodopa; dyskinesia; methamphetamine;

    Sammanfattning : The motor deficits seen in Parkinson’s disease (PD) are the result of a loss of catecholaminergic neurons from the substantia nigra (SN) and the associated loss of striatal dopamine. Clinical signs become evident once striatal dopamine levels decline by at least 70-80% and nigral cell numbers by 40%, and worsen with increased duration of the disease. LÄS MER