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Visar resultat 6 - 10 av 39 avhandlingar som matchar ovanstående sökkriterier.

  1. 6. Multivariate processing and modelling of hyphenated metabolite data

    Författare :Pär Jonsson; Michael Sjöström; Royston Goodacre; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemometrics; Curve Resolution; GC MS; LC MS; Metabolomics; Metabonomics; Multivariate Analysis and Multivariate Curve Resolution.; Organic chemistry; Organisk kemi;

    Sammanfattning : One trend in the ‘omics’ sciences is the generation of increasing amounts of data, describing complex biological samples. To cope with this and facilitate progress towards reliable diagnostic tools, it is crucial to develop methods for extracting representative and predictive information. LÄS MER

  2. 7. New methods for determination of airborne pollutants : Focus on tetrabromobisphenol A, organophosphate triesters and polycyclic aromatic hydrocarbons

    Författare :Johanna Tollbäck; Ulrika Nilsson; Peter Haglund; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Air sampling; sampling methods; indoor air; SPE; SPME; extraction; dynamic extraction; online coupling; SWE; subcritical water extraction; GC MS; LC MS; organophosphate triesters; PAH; tetrabromobisphenol A; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Sammanfattning : The work presented in this thesis concerns the development and evaluation of new methods of sampling and analysis of organic pollutants in the indoor and outdoor environment. In Paper I, the development of a new method was reported for the determination of the brominated flame retardant tetrabromobisphenol A (TBBPA) in air using sampling with glass fiber filter and polyurethane foam (PUF), ultrasonic solvent extraction and liquid chromatography coupled to electrospray ionisation mass spectrometry (LC-ESI/MS). LÄS MER

  3. 8. Targeted and untargeted analysis of organic contaminants from on-site sewage treatment facilities : Removal, fate and environmental impact

    Författare :Kristin Blum; Peter Haglund; Patrik Andersson; Pim Leonards; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; decentralized sewage treatment; wastewater; surface water; environmental fate; bioavailability; removal efficiency; mass fluxes; biochar; environment; GC×GC-MS; LC-IM-MS; mass spectrometry; contaminants; pollutants; prioritization; non-target analysis; screening; analytisk kemi; Analytical Chemistry;

    Sammanfattning : On-site sewage treatment facilities (OSSFs) are widely used all over the world to treat wastewater when large-scale sewage treatment plants (STPs) are not economically feasible. Although there is great awareness that the release of untreated wastewater into the environment can lead to water-related diseases and eutrophication, little is known about organic contaminants and their removal by OSSFs, environmental load and fate. LÄS MER

  4. 9. Methods for Determination of Benzo(a)pyrene and High Molecular Weight (>300 Da) Polycyclic Aromatic Hydrocarbons in Particulate Matter from Ambient Air and Vehicle Exhausts

    Författare :Christoffer Bergvall; Roger Westerholm; Stephen Wise; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PAH; dibenzopyrene; benzo a pyrene; standard reference material; air particulate matter; diesel particulate matter; toxic equivalence factor; ultrasonic assisted extraction; accelerated solvent extraction; automation; online coupling; GC MC; LC GC MS; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Air pollution with particulate matter (PM) raises considerable concern because of its adverse effects on human health. For this reason, and because the mechanisms of PM toxicity are not fully known, there is an urgent need to determine the chemical constituents of atmospheric PM, especially PM emanating from traffic - a major source of urban PM. LÄS MER

  5. 10. Analytical studies of morphine and related substances using LC-MS/MS

    Författare :Maria Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Morphine is considered to be metabolized in three distinct metabolic pathways; glucuronidation, sulfation and N-demetylation. However, identification of morphine-3-sulfate (M3S) and morphine-6-sulfate (M6S) as morphine metabolites has not been convincing according to previous literature due to lack of reliable reference material and identification based on thin layer chromatography. LÄS MER