Sökning: "Pär Jonsson"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Pär Jonsson.

  1. 1. Multivariate processing and modelling of hyphenated metabolite data

    Författare :Pär Jonsson; Michael Sjöström; Royston Goodacre; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemometrics; Curve Resolution; GC MS; LC MS; Metabolomics; Metabonomics; Multivariate Analysis and Multivariate Curve Resolution.; Organic chemistry; Organisk kemi;

    Sammanfattning : One trend in the ‘omics’ sciences is the generation of increasing amounts of data, describing complex biological samples. To cope with this and facilitate progress towards reliable diagnostic tools, it is crucial to develop methods for extracting representative and predictive information. LÄS MER

  3. 2. In search of early biomarkers in pancreatic ductal adenocarcinoma using multi-omics and bioinformatics

    Författare :Emmy Borgmästars; Malin Sund; Ola Billing; Pär Jonsson; Zelmina Lubovac-Pilav; Oskar Franklin; Stefan Enroth; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Pancreatic cancer; microRNA functional analysis; TPS; miRNomics; metabolomics; proteomics; plasma samples; early detection; risk; survival;

    Sammanfattning : Background: Pancreatic ductal adenocarcinoma (PDAC) is a very aggressive malignancy with a 5-year survival of 10 %. Surgery is the only curative treatment. Unfortunately, few patients are eligible for surgery due to late detection. Thus, we need ways to detect the disease at an earlier stage and for that good screening biomarkers could be used. LÄS MER

  4. 3. Some Aspects on Macroscopic Mixing in a Tundish

    Författare :Chao Chen; Anders Tilliander; Lage Jonsson; Pär Jönsson; Guoguang Cheng; Seppo Louhenkilpi; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; continuous reactor; tundish; tracer; macroscopic mixing; water model; CFD; turbulence models; inclusions removal; inclusions deposition; dynamic removal; Materials Science and Engineering; Teknisk materialvetenskap;

    Sammanfattning : Two aspects on macroscopic mixing in a continuous flow system – metallurgical tundish were studied. Specifically, 1) the first focus was on salt solution tracer mixing, which is important for tundish design from perspectives of tracer technology and Residence Time Distributions (RTD) as well as for the understanding of the macroscopic mixing in tundishes. LÄS MER

  5. 4. Early diagnosis and treatment of prostate cancer : observational studies in the National Prostate Cancer Register of Sweden and the Västerbotten Intervention Project

    Författare :Benny Holmström; Pär Stattin; Håkan Jonsson; Mattias Johansson; Gunnar Aus; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; prostate-specific antigen; single nucleotide polymorphism; Urology and andrology; Urologi och andrologi; Urology; kirurgi; särskilt urologi;

    Sammanfattning : Prostate-specific antigen (PSA) testing has caused a steep increase in the incidence of prostate cancer, especially the incidence of localised low risk disease. In order to decrease the overdiagnosis accompanied by PSA testing, analysis of inherited genetic variants have been suggested as potential tools for clinical assessment of disease risk. LÄS MER

  7. 5. Metabolic factors and risk of prostate, kidney, and bladder cancer

    Författare :Christel Häggström; Pär Stattin; Håkan Jonsson; Tanja Stocks; Bas Bueno de Mesquita; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cohort study; competing risk; epidemiology; metabolic factors; prostate cancer; kidney cancer; bladder cancer; renal cell carcinoma; survival analysis; Epidemiology; epidemiologi; Urology; kirurgi; särskilt urologi; onkologi; Oncology;

    Sammanfattning : Background: Prostate cancer is the most common cancer in Sweden with around 10,000 new cases every year. Kidney and bladder cancer are less common with 1,000 and 2,000 new cases annually, respectively. LÄS MER