Sökning: "Chemometrics"

Visar resultat 1 - 5 av 43 avhandlingar innehållade ordet Chemometrics.

  1. 1. Variance Reduction in Analytical Chemistry New Numerical Methods in Chemometrics and Molecular Simulation

    Detta är en avhandling från Stockholm : Institutionen för analytisk kemi

    Författare :K. Magnus Åberg; Stockholms universitet.; [2004]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; chemometrics; pulse-coupled neural networks; peak alignment; class separability; molecular dynamics; Monte Carlo; expanded ensembles; free energy; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi;

    Sammanfattning : This thesis is based on five papers addressing variance reduction in different ways. The papers have in common that they all present new numerical methods. LÄS MER

  2. 2. Aspects of Optimisation of Separation of Drugs by Chemometrics

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Valérie Harang; Uppsala universitet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; optimisation; separation; chemometrics; high performance liquid chromatography; electrodriven techniques; microemulsion electrokinetic chromatography; statistical experimental design; molecular modelling; chiral separation; cellobiohydrolase; Farmaceutisk kemi; PHARMACY Pharmaceutical chemistry; FARMACI Farmaceutisk kemi;

    Sammanfattning : Statistical experimental designs have been used for method development and optimisation of separation. Two reversed phase HPLC methods were optimised. LÄS MER

  3. 3. Development of Protocols for Metabolomics in Biomedical Research using Chemometrics

    Detta är en avhandling från Department of Chemistry, Lund University

    Författare :Anders Danielsson; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mass spectrometry; gas chromatography; design of experiments; Metabolomics; chemometrics; diabetes; metabolism; multivariate analysis;

    Sammanfattning : Metabolomics is a rapidly growing research field. It aims for quantification of all the metabolites in a biological sample such as plasma, saliva, cerebrospinal fluid or cells. LÄS MER

  4. 4. Advances in Separation Science . Molecular Imprinting: Development of Spherical Beads and Optimization of the Formulation by Chemometrics

    Detta är en avhandling från Stockholm : Institutionen för analytisk kemi

    Författare :Henrik Kempe; Stockholms universitet.; [2007]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chromatography; Parameter estimation; Diffusion; Molecularly imprinted polymer; Suspension polymerization; Chemometrics; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi;

    Sammanfattning : An intrinsic mathematical model for simulation of fixed bed chromatography was demonstrated and compared to more simplified models. The former model was shown to describe variations in the physical, kinetic, and operating parameters better than the latter ones. LÄS MER

  5. 5. Methods for structural studies of an antibody, screening metabolites in rat urine and analysis of spent cell cultivation media using LC/ESI-MS and chemometrics

    Detta är en avhandling från Stockholm : Department of Analytical Chemistry, Stockholm University

    Författare :Leila Zamani; Stockholms universitet.; [2009]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Screening; Fingerprinting; metabolomics; Protein drugs; Mammalian Cell lines; LC ESI-MS; chemometrics; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi; analytisk kemi; Analytical Chemistry;

    Sammanfattning : This thesis describes bioanalytical methods for generating fingerprints of biological systems for extracting relevant information with (protein) drugs in focus. Similarities and differences between samples can reveal the hidden relevant information, which can be used to optimize the production and facilitate the quality control of such protein drugs during their development and manufacture. LÄS MER