Sökning: "IL-1beta"
Visar resultat 1 - 5 av 70 avhandlingar innehållade ordet IL-1beta.
1. Metabolic alterations in patients with self-inflicted aggressive behaviour
Sammanfattning : Self-inflicted aggressive behaviour is a cross diagnostic phenomenon of major clinical relevance in psychiatric setting. Accumulating evidence speaks for a role of metabolic and immunological factors in aggressive behaviour. LÄS MER
2. Molecular targets for glucocorticoids in macrophages: cytosolic phospholipase A2 and cytokine formation
Sammanfattning : The aim of this investigation has been to study mechanisms by which glucocorticoids inhibit inflammatory processes in vitro. Type IV cytosolic 85 kDa phospholipase A2 (cPLA2) is an important modulator of inflammatory responses that is present in macrophages as well as in other cell types. LÄS MER
3. Molecular mechanisms and immunomodulatory approaches in acute cystitis
Sammanfattning : hand in the fight against resistant microbes. This thesis discusses the feasibility and potential of specific immunotherapy in treating acute bacterial infections and chronic sequels. The infection model is acute cystitis; the most common form of urinary tract infection, affecting millions of patients annually. LÄS MER
4. Regulation of inducible nitric oxide synthase - Consequences in experimental models of bladder disease
Sammanfattning : Inducible nitric oxide synthase (iNOS) expression is associated with various pathophysiological conditions in the lower urinary tract. The aims of this thesis have been to investigate the regulation of iNOS in bladder smooth muscle cells and the consequences on neuromuscular regulation, cell growth and differentiation. LÄS MER
5. On the effects of Streptococcal NAD+-glycohydrolase and Streptolysin O on macrophages
Sammanfattning : SummaryThe human pathogen Streptococcus pyogenes (GAS) causes both superficial infections, such as strep throat, and invasive infections, such as necrotizing fasciitis, and is responsible for about half a million deaths each year. The number of GAS infections have increased since the 1980’s, due to the emergence of a M1T1 strain that has become widely disseminated. LÄS MER