Sökning: "HIV"

Visar resultat 31 - 35 av 644 avhandlingar innehållade ordet HIV.

  1. 31. Development of novel molecular and microfluidics tools for identification and characterization of latent HIV-1 reservoir

    Författare :Wang Zhang; Aman Russom; Ujjwal Neogi; Afshin Ahmadian; Utkan Demirci; KTH; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; Latent HIV-1 reservoir; HIV-1 characterization; Microfludics; Molecular detection; Medical Technology; Medicinsk teknologi;

    Sammanfattning : The existence of latent HIV-1 reservoir (LR) in all HIV-1 infected patients serves as a major obstacle to completely cure HIV-1 infection. However, up to now there is still no available assay that provides an accurate measurement of the reservoir size. LÄS MER

  3. 32. Structure-aided design of antiviral drugs : Application of the method on HIV-1 protease and SIV reverse transcriptase

    Författare :Hans Ola Andersson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; HIV; protease; SIV; reverse transcriptase; structure; inhibitor; drug design; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Many efforts have been made to control the AIDS epidemic. Extensive studies have been done on the biology, biochemistry, and structural biology of HIV in the search for antiviral drugs. The viral-encoded enzymes reverse transcriptase and protease have been main targets for drug design. LÄS MER

  4. 33. Tertiary Alcohol- or β-Hydroxy γ-Lactam-Based HIV-1 Protease Inhibitors : Microwave Applications in Batch and Continuous Flow Organic Synthesis

    Författare :Per Öhrngren; Mats Larhed; Knud J. Jensen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; HIV; AIDS; protease inhibitor; aspartic protease; lactam; tertiary alcohol; continuous-flow; microwave; non-resonant; MAOS; Medicinal Chemistry; Läkemedelskemi;

    Sammanfattning : Since the outbreak of the HIV/AIDS pandemic in the 1980s, the disease has cost the lives of over 30 million people, and a further 33 million are currently living with the HIV infection. With the appropriate treatment, HIV/AIDS can today be regarded as a chronic but manageable disease. LÄS MER

  5. 34. Antiretroviral treatment of HIV-1 in Sweden with focus on virological aspects

    Författare :Erik Sörstedt; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; antiretroviral therapy; transient viremia; viral blip; nucleoside transcriptase inhibitor resistance; dolutegravir; baseline viral load; HIV RNA; virological failure;

    Sammanfattning : From a clinical standpoint, there are many factors to consider when optimizing the care for people living with HIV (PLWH). With help from clinical guidelines, most obstacles can be addressed. Expanded knowledge is however in constant demand, from local conditions to universal processes. LÄS MER

  7. 35. Bortom oskuldens tid : En etnologisk studie av moral, trygghet och otrygghet i skuggan av hiv

    Författare :Anna Ljung; Susanne Lundin; Uppsala universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Ethnology; ethnology; HIV; AIDS; representations; moral; moral crisis; safety; insecurity; embodiment; death; suffering; control; life-strategies; discourse; Etnologi; Ethnology; Etnologi; Etnologi; Ethnology;

    Sammanfattning : The purpose of this doctoral thesis is to investigate how the Swedish press coverage of AIDS reflects cultural assumptions about morals, security and insecurity and how these representations affect the lives of people who are HIV-positive. It is clear that HIV-positive people are affected by such representations. LÄS MER