Sökning: "Carbohydrate Metabolism"

Visar resultat 11 - 15 av 92 avhandlingar innehållade orden Carbohydrate Metabolism.

  1. 11. Hormone-Sensitive Lipase, new roles for an old enzyme

    Författare :Ola Hansson; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes; Vitamin A; Inflammation; Medicine human and vertebrates ; Medicin människa och djur ; Metabolism; Hormone-Sensitive Lipase; Proteomics; Obesity; White adipose tissue; Skeletal muscle;

    Sammanfattning : Hormone-sensitive lipase (HSL) has a wide tissue distribution with the highest expression found in white adipose tissue (WAT). HSL also has a unique ability to hydrolyze a large panel of substrates including acylglycerols, cholesteryl esters and retinyl esters. HSL is potentially a new drug target for the treatment of obesity and type II diabetes. LÄS MER

  2. 12. Plant UDP-glucose Pyrophosphorylase : Function and Regulation

    Författare :Meng Meng; Leszek Kleczkowski; Javier Pozueta-Romero; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; UDP-glucose pyrophosphorylase; carbohydrate metabolism; in vivo regulation; T-DNA knockout; heterologous expression; isozyme; mutagenesis; kinetic property; oligomerization; Plant physiology; Växtfysiologi;

    Sammanfattning : UDP-glucose pyrophosphorylase (UGPase) is an important enzyme of carbohydrate metabolism in all living organisms. The main aim of this thesis was to investigate the function and regulation of plant UGP genes as well as the UGPase proteins. LÄS MER

  3. 13. The effect of protein intake and physical exercise on energy turnover and substrate utilisation at energy balance in man

    Författare :Anders H. Forslund; Uppsala universitet; []
    Nyckelord :Medical sciences; Body composition; carbohydrate; energy turnover; fat; protein; stable isotopes; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Nutrition; näringslära;

    Sammanfattning : The principal goal of the thesis has been to evaluate the effect of protein intake and physical exercise on energy turnover and substrate utilisation. Body composition assessment is of importance as an indicator of the energy balance. Therefore, in the first study the aim was to develop new models to estimate body composition more accurately. LÄS MER

  4. 14. Glycerol kinase deficiency. Clinical, biochemical, and genetic aspects

    Författare :Christina Hellerud; Göteborgs universitet; []
    Nyckelord :contiguous gene syndrome; diagnose; exercise; fasting; glucose deficit; glycerol; glycerol kinase deficiency; metabolism; molecular modelling; mRNA analysis; mutation; natural history; prognosis; splice-junction analysis; treatment; triglycerides;

    Sammanfattning : Glycerol kinase deficiency (GKD, MIM 307030) is an X-linked recessive inborn error of metabolism occurring isolated or in an Xp contiguous gene syndrome with adrenal hypoplasia and/or Duchenne muscular dystrophy. The gene syndrome is due to deletions in the p21 region on the X chromosome. LÄS MER

  5. 15. Neuropeptides and GABA in control of insulin producing cells in Drosophila

    Författare :Jeannette Söderberg; Åsa Winther; Dick R. Nässel; Susan Broughton; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; insulin signaling; metabolism; feeding; DTK; DSK; GABA; stress resistance; funktionell zoomorfologi; Functional Zoomorphology;

    Sammanfattning : Insulin plays an important role in metabolic regulation as well as in growth, fecundity and stress resistance. In order to understand more about the regulation of insulin-like peptide (DILP) production and release we investigate the impact of neuropeptide (DTK) signaling and classical neurotransmitter (GABA) signaling onto the insulin producing cells of the Drosophila brain. LÄS MER