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Visar resultat 1 - 5 av 18 avhandlingar som matchar ovanstående sökkriterier.
1. Antibiotic uptake in Gram-negative bacteria
Sammanfattning : The increasing emergence and spread of antibiotic-resistant bacteria is a serious threat to public health. Of particular concern are Gram-negative bacteria such as Escherichia coli, Acinetobacter baumannii, Klebsiella pneumoniae or Pseudomonas aeruginosa. LÄS MER
2. Design, synthesis and evaluation of bacterial sialic acid uptake inhibitors
Sammanfattning : Antibiotic resistance is a major threat for our society and finding novel antibacterial therapies is of greatimportance. In this thesis, we investigate bacterial sialic acid uptake inhibitors as a novel antibacterial approach.Bacteria do not biosynthesise sialic acid and therefore harvest it from the host. LÄS MER
3. Antibiotic resistance and pathogenesis of Streptococci with focus on Group A Streptococci
Sammanfattning : Multi-drug resistant (MDR) infections remain the leading cause of death worldwide. MDR infections caused by Streptococcus pneumoniae (Spn), Streptococcus pyogenes (GAS) and Streptococcus agalactiae (GBS) are considered global threats to human health due to increased spread of antibiotic resistance and limited treatment options. LÄS MER
4. Novel inhibitors of Chlamydia trachomatis virulence
Sammanfattning : Chlamydia trachomatis is an obligate intracellular bacterium that infects over 100 million people globally every year. Chlamydia infections can be persistent, cause infertility and blindness, adding an economical burden in the healthcare systems. LÄS MER
5. Characterization and persistence of potential human pathogenic vibrios in aquatic environments
Sammanfattning : Vibrio spp., natural inhabitants of aquatic environments, are one of the most common causes of bacterial gastroenteritis in the world, being spread to humans via the ingestion of seafood, contaminated drinking water or exposure to seawater. The majority of Vibrio spp. are avirulent, but certain strains may sporadically be human pathogenic. LÄS MER