Visar resultat 1 - 5 av 211 avhandlingar innehållade ordet Lipopolysaccharide.
Sammanfattning : The present thesis focuses on the vascular effects of antimicrobial peptides especially mechanisms involving the vasodilator nitric oxide (NO), which is released from the blood vessel wall during inflammatory conditions such as sepsis. Bacterial lipopolysaccharide stimulates the expression of nitric oxide synthase (iNOS), which increases the NO production in vascular tissues or cultured vascular smooth muscle cells (VSMC). LÄS MER
Sammanfattning : This study investigated the pathogenesis of hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). (1) The relative roles of lipopolysaccharide and Shiga-like toxin-2 were studied in a mouse model of Escherichia coli O157:H7 infection. LÄS MER
3. Physiology of Escherichia coli in batch and fed-batch cultures with special emphasis on amino acid and glucose metabolism
Sammanfattning : The objective of this work is to better understand themetabolism and physiology ofEscherichiacoli(W3110) in defined medium cultures with thelong-term goal of improving cell yield and recombinant proteinproductivity.The order of amino acid utilization inE. colibatch cultures was investigated in a medium with16 amino acids and glucose. LÄS MER
4. Modulating Organ Dysfunction in Experimental Septic Shock : Effects of Aminoglycosides, Antiendotoxin Measures and Endotoxin Tolerance
Sammanfattning : Sepsis is a common diagnose in the intensive care population, burdened with a high mortality. The systemic inflammatory reaction underlying the development of septic organ dysfunction can be modeled using Gram-negative bacterial lipopolysaccharide, endotoxin. LÄS MER
Sammanfattning : The immune system protects the host against pathogens by distinguishing self from non-self. However, it is most-often disregarded in pharmacokinetic-pharmacodynamic (PKPD) characterization of (new and old) antibiotics. LÄS MER