Sökning: "Åsa Gylfe"

Hittade 3 avhandlingar innehållade orden Åsa Gylfe.

  1. 1. Role of birds in the biology of Lyme disease Borrelia

    Författare :Åsa Gylfe; Klaus Kurtenbach; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lyme disease; birds; Borrelia; I. uriae; infection reactivation; stress; bipolar distribution; transequatorial transport;

    Sammanfattning : Lyme disease is a tick-transmitted illness caused by Borrelia burgdorferi sensu lato (s.l.), a group of spirochetes with at least three human pathogenic species, B. burgdorferi sensu stricto, B. LÄS MER

  3. 2. Novel inhibitors of Chlamydia trachomatis virulence

    Författare :Carlos Nunez-Otero; Åsa Gylfe; Sven Bergström; Fredrik Almqvist; Jörgen Johansson; Patrik Bavoil; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chlamydia trachomatis; 2-pyridone; small molecules; KSK213; Structure-Activity Relationships SAR ; antibiotic resistance; target identification; transcription; RNA; progeny; infectivity;

    Sammanfattning : Chlamydia trachomatis is an obligate intracellular bacterium that infects over 100 million people globally every year. Chlamydia infections can be persistent, cause infertility and blindness, adding an economical burden in the healthcare systems. LÄS MER

  4. 3. Controlled release gel formulations and preclinical screening of drug candidates

    Författare :Tofeeq Ur-Rehman; Gerhard Gröbner; Mikael Elofsson; Åsa Gylfe; Martin Malmsten; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; poloxamer; drug delivery; micellization; DMSO; calorimetry; NMR. in situ gelation; chitosan; preclinical pharmacokinetics; type III secretion inhibitors; Physical chemistry; Fysikalisk kemi; Pharmaceutics; galenisk farmaci;

    Sammanfattning : Simple gel formulations may be applied to enhance the systemic and local exposure of potential compounds. The aim of this thesis is the development and characterization of controlled release formulations based on thermo-reversible poloxamer gels, which are suitable for novel drug delivery applications. LÄS MER