Sökning: "Daniel Daley"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Daniel Daley.

  1. 1. Exploring the Interplay of Lipids and Membrane Proteins

    Författare :Candan Ariöz; Åke Wieslander; Daniel O. Daley; Malcolm East; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; Membrane lipids; membrane proteins; anionic lipids; membrane remodeling; intracellular vesicles; model membrane systems; glycosyltransferase; Escherichia coli; lipid composition; fatty acid modification; membrane curvature; bacterial homeoviscous adaptation; biokemi; Biochemistry;

    Sammanfattning : The interplay between lipids and membrane proteins is known to affect membrane protein topology and thus have significant effect (control) on their functions. In this PhD thesis, the influence of lipids on the membrane protein function was studied using three different membrane protein models. LÄS MER

  2. 2. Protein trafficking in the cell envelope of Escherichia coli : Identification and characterisation of a novel chaperone

    Författare :Hansjörg Götzke; Daniel Daley; Hans-Georg Koch; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Sammanfattning : The cell envelope of Gram-negative bacteria, like Escherichia coli, is composed of a cytoplasmic membrane, a periplasmic space containing a peptidoglycan layer and an outer membrane. About 30 % of all proteins are localised in the cell envelope. LÄS MER

  3. 3. Engineering microbial cell factories for protein production

    Författare :Kiavash Mirzadeh; Daniel Daley; Grzegorz Kudla; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Protein production; expression vector; recombinant DNA; Translation initiation region; Escherichia coli; mRNA secondary structure; Synthetic evolution; biokemi; Biochemistry;

    Sammanfattning : Proteins are often produced using microbial cell factories for academic or industrial purposes. Protein production is however not an open-and-shut procedure. Production yields often vary in an unpredictable and context dependent manner, limiting the rational design of a straightforward production experiment. LÄS MER

  4. 4. Antibiotic uptake in Gram-negative bacteria

    Författare :Claudio Muheim; Daniel Daley; Jean-Marie Pagès; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Gram-negative bacteria; Antibiotic uptake; Outer membrane; Lipopolysaccharide; biokemi; Biochemistry;

    Sammanfattning : The increasing emergence and spread of antibiotic-resistant bacteria is a serious threat to public health. Of particular concern are Gram-negative bacteria such as Escherichia coli, Acinetobacter baumannii, Klebsiella pneumoniae or Pseudomonas aeruginosa. LÄS MER

  5. 5. The social life of a membrane protein; It's complex

    Författare :Isolde Palombo; Daniel Daley; Said Eshaghi; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; membrane proteins; assembly; cofactors; magnesium; Escherichia coli; biokemi; Biochemistry;

    Sammanfattning : Membrane proteins are key players in many biological processes. Since most membrane proteins are assembled into oligomeric complexes it is important to understand how they interact with each other. Unfortunately however, the assembly process (i.e. LÄS MER