Sökning: "5-HT receptors"

Visar resultat 11 - 15 av 61 avhandlingar innehållade orden 5-HT receptors.

1. 11. Unusual vascular responses in the umbilical artery, mediated by endothelin-like receptors

   Författare :Maria Laursen; Urogynekologi och reproduktionsfarmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reproduction; sexuality; Obstetrik; gynekologi; andrologi; sexualitet; andrology; gynaecology; Obstetrics; Medicin människa och djur ; Medicine human and vertebrates ; unusual vascular responses; endothelin-like receptors; human umbilical artery; reproduktion;

   Sammanfattning : In this present study the population of endothelin-like receptors in the human umbilical artery was examined in vitro in different parts of the umbilical cord. Immunohistochemistry revealed ETB receptors in the endothelium and an uneven distribution of ETA receptors in the smooth muscle of the arterial wall, when comparing different parts of the umbilical artery. LÄS MER

3. 12. Messenger molecules and receptors in the human trigeminovascular system

   Författare :Mingyan Hou; Lund Medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; Neurologi; neurofysiologi; Neurology; neuropsychology; neurophysiology;

   Sammanfattning : The initiation of a migraine attack involves a primary central nervous system dysfunction with subsequent activation of the trigeminovascular system. In trigeminal ganglia, the expression of calcitonin gene-related peptide (CGRP), substance P (SP) and nitric oxide synthase (NOS) have been demonstrated by immunocytochemistry. LÄS MER

4. 13. 5-HT1A receptor ligands with putative antidepressant activity : pharmacological studies in the rat

   Författare :Lotta Arborelius; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :antidepressants; citalopram; dopamine; dorsal raphe nucleus; electrophysiology; frontal cortex; 5-HT; A receptors; microdialysis; serotonin; rat;

   Sammanfattning : Several studies suggest that serotonin (5-hydroxytryptamine, 5-HT)IA receptor agonists possess antidepressant activity. Probably these agents exert their therapeutic effect through stimulation of postsynaptic 5-HT,A receptors. LÄS MER

5. 14. Neuropeptides in the human postmortem brain : focus on galanin and its receptors in depression

   Författare :Swapnali Barde; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Neuropeptides represent the most diverse family of messenger molecules in the nervous system, which are co-expressed with key neurotransmitters in several brain regions. They modulate synaptic neurotransmission and have, in some cases, also trophic functions. One such neuropeptide, and the focus of the thesis, is ‘galanin’. LÄS MER

7. 15. Serotonergic receptor subtypes in learning and memory : focus on 5-HT1A, 5-HT1B and 5-HT2A receptors

   Författare :Maria Lüttgen; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Serotonin; 5-HT1A receptor; 5-HT1B receptor; 5-HT2A receptor; acetylcholine; NMDA receptor; water maze; passive avoidance; septum; hippocampus; teaming; memory; immunohistochemistry; mRNA;

   Sammanfattning : The aim of this thesis was to study how serotonin (5-HT) receptor subtypes can influence hippocampus/amygdala-dependent teaming and memory using the water maze (WM) and the passive avoidance (PA) tasks in rodents, and to provide a cellular correlate to the behavioral results using histochemical methods. Glutamatergic neurons in the trisynaptic circuit of the hippocampus are believed to be important for spatial teaming and memory as well as synaptic plasticity. LÄS MER