Sökning: "NMDA receptor"

Visar resultat 1 - 5 av 121 avhandlingar innehållade orden NMDA receptor.

  1. 1. Neurosteroids Induce Allosteric Effects on the NMDA Receptor Nanomolar Concentrations of Neurosteroids Exert Non-Genomic Effects on the NMDA Receptor Complex

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Tobias Johansson; Uppsala universitet.; [2008]
    Nyckelord :Pharmaceutical pharmacology; Pharmacology; neurosteroids; NMDA receptor; NR2B subunit; ifenprodil; sigma receptor; anabolic androgenic steroids; allosteric modulation; non-genomic; Farmaceutisk farmakologi;

    Sammanfattning : The neurosteroids constitute a group of powerful hormones synthesized and acting in the central nervous system. They participate in a number of important central processes, such as memory and learning, mood and neuroprotection. LÄS MER

  2. 2. Developmental plasticity of the glutamate synapse: Roles of low frequency stimulation, hebbian induction and the NMDA receptor

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Joakim Strandberg; Göteborgs universitet.; Gothenburg University.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AMPA receptor; Development; Glutamate; Hippocampus; Long-term depression; Long-term potentiation; NMDA receptor; Synaptic depression;

    Sammanfattning : The glutamate synapse is by far the most common synapse in the brain and acts via postsynaptic AMPA, NMDA and mGlu receptors. During brain development there is a continuous production of these synapses where those partaking in activity resulting in neuronal activity are subsequently selected to establish an appropriate functional pattern of synaptic connectivity while those that do not are elimimated. LÄS MER

  3. 3. Development and Characterization of a Global Brain Ischemia Model in the Mouse -A Genetic and Pharmacological Approach

    Detta är en avhandling från Division IV

    Författare :Tomas Olsson; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurofysiologi; neuropsykologi; Neurologi; neuropsychology; Neurology; global; hypothermia; hsp70; receptor; adenosine A1; NMDA; cystatin C; cell death; hippocampus; Brain; ischemia; neurophysiology;

    Sammanfattning : Brain ischemia is a major cause of death and morbidity in the industrialized countries. It is mainly caused by stroke, but may also be the consequence of successful cardiopulmonary resuscitation in victims of cardiac arrest, known as transient global ischemia. LÄS MER

  4. 4. Modulation of the Progenitor Cell and Homeostatic Capacities of Müller Glia Cells in Retina Focus on α2-Adrenergic and Endothelin Receptor Signaling Systems

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Mohammad Harun-Or-Rashid; Uppsala universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alpha2-adrenergic receptor; Brimonidine; Brn3a; Dedifferentiation; Endothelin; EGFR; ERK1 2; Neuroprotection; NMDA; MIO-M1 human Müller cell; Müller cells; Retina; Retinal ganglion cells; Src-kinase; Transactivation.; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Müller cells are major glial cells in the retina and have a broad range of functions that are vital for the retinal neurons. During retinal injury gliotic response either leads to Müller cell dedifferentiation and formation of a retinal progenitor or to maintenance of mature Müller cell functions. LÄS MER

  5. 5. Plasticity and variation of synaptic responses in hippocampus. Role of AMPA and NMDA receptors

    Detta är en avhandling från Göteborg

    Författare :Yin-Ping Niu; Göteborgs universitet.; Gothenburg University.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; learning and memory; synaptic plasticity; hippocampus; synapse; AMPA receptor; NMDA receptor; LTP; LTD; CV; TFS;

    Sammanfattning : It is generally believed that synaptic plasticity in the central nervous system may underlie learning and memory as well as neuronal development. The most wellstudied examples of such synaptic plasticity are long-term potentiation (LTP) andlong-term depression (LTD). LÄS MER