Sökning: "yeast cell"

Visar resultat 31 - 35 av 382 avhandlingar innehållade orden yeast cell.

1. 31. Cell-penetrating peptides : Uptake, stability and biological activity

   Författare :Tina Holm; Ülo Langel; Roland Brock; Stockholms universitet; []
   Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

   Sammanfattning : Cell-penetrating peptides (CPPs) have emerged as a group of remarkable delivery vectors for various hydrophilic macromolecules, otherwise excluded from cells due to the protective plasma membrane. Unbiased conclusions regarding e.g. LÄS MER

3. 32. Constraint-based modeling of metabolism - interpreting predictions of growth and ATP synthesis in human and yeast

   Författare :Avlant Nilsson; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; the Crabtree effect; enzyme-constraints; stunting; cellular economy; the Warburg effect; uncoupling; tumor; flux balance analysis; lactate threshold; metabolite depletion;

   Sammanfattning : Growth is the primary objective of the cell. Diseases arise when cells diverge from a healthy growth-pattern. An increased understanding of cellular growth may thus be translated into improved human health. The cell requires materials and free energy (in the form of ATP) in order to grow, metabolism supplies the cell with this. LÄS MER

4. 33. DNA precursor asymmetries, Mismatch Repair and their effect on mutation specificity

   Författare :Robert Buckland; Andrei Chabes; Juan Méndez; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA Replication Fidelity; Mutations; dNTP pools; Mismatch Repair; Checkpoint; Ribonucleotide Reductase; Msh2; medicinsk biokemi; Medical Biochemistry; molekylärbiologi; Molecular Biology;

   Sammanfattning : In order to build any structure, a good supply of materials, accurate workers and quality control are needed. This is even the case when constructing DNA, the so-called “Code of Life.” For a species to continue to exist, this DNA code must be copied with incredibly high accuracy when each and every cell replicates. LÄS MER

5. 34. Functional studies of Mediator in Arabidopsis thaliana and Saccharomyces cerevisiae

   Författare :Nils Elfving; Stefan Björklund; Jesper Svejstrup; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transcriptional regulation; chromatin; stress; Pol II; mediator; DREB2A; ZFHD1; MYB-like; Msn2; molekylärbiologi; Molecular Biology;

   Sammanfattning : Mediator has been shown to be essential for regulation of RNA Polymerase II mediated transcription. Mediator functions as an interface between the general transcriptional machinery and a multitude of DNA binding transcriptional regulators, although the molecular mechanism for the process is elusive. LÄS MER

7. 35. Metal homeostasis as critical determinant for cellular fitness

   Författare :Jutta Diessl; Sabrina Büttner; Rajini Rao; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; metal homeostasis; manganese toxicity; coenzyme Q synthesis; mitochondrial respiration; calcineurin signaling; Pmr1; SPCA1; calcium; survival; caloric restriction; Parkinson’s disease models; proteotoxicity; Pep4; cathepsin D; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : Metals play a crucial role in cellular biology. Bulk and trace metals such as calcium and manganese regulate a plethora of cellular processes ranging from signaling and oxidative stress to proteostasis and energy metabolism. LÄS MER