Sökning: "Pep4"

Hittade 2 avhandlingar innehållade ordet Pep4.

  1. 1. Metal homeostasis as critical determinant for cellular fitness

    Författare :Jutta Diessl; Sabrina Büttner; Rajini Rao; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; metal homeostasis; manganese toxicity; coenzyme Q synthesis; mitochondrial respiration; calcineurin signaling; Pmr1; SPCA1; calcium; survival; caloric restriction; Parkinson’s disease models; proteotoxicity; Pep4; cathepsin D; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Metals play a crucial role in cellular biology. Bulk and trace metals such as calcium and manganese regulate a plethora of cellular processes ranging from signaling and oxidative stress to proteostasis and energy metabolism. LÄS MER

  2. 2. Functional characterization of the yeast ER packaging chaperone Shr3p

    Författare :Fredrik Gilstring; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : All living cells are enclosed by a plasma membrane (PM). The PM is a dynamic structure comprised of lipids and proteins that establishes and maintains the integrity of the cell. Cells utilize the PM to regulate metabolism by selectively altering the flow of metabolites entering the cell. The integral protein components of the PM, e. LÄS MER