Sökning: "Pol II"

Visar resultat 1 - 5 av 59 avhandlingar innehållade orden Pol II.

1. 1. Reasons for All Seasons : An Outline of Rationalist View of Moral Concepts

   Författare :Tomasz Pol; Ingmar Persson; Uppsala universitet; []
   Nyckelord :HUMANIORA; HUMANITIES; Philosophy; moral concepts; the Reconciliation Problem; ethical rationalism; rational requirements; reflective agency; the Aristokantian proposal; generic deontic rules; Filosofi; Philosophy subjects; Filosofiämnen; Practical Philosophy; praktisk filosofi;

   Sammanfattning : The aim of this thesis is to provide an adequate view of moral concepts. The major obstacle that stands in the way of providing such a view is the problem of combining two general features of moral judgments that seem to be constitutive of their meaning, namely objectivity and practical significance. LÄS MER

3. 2. Inverse problems in signal processing : Functional optimization, parameter estimation and machine learning

   Författare :Pol del Aguila Pla; Joakim Jaldén; Yonina C. Eldar; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; inverse problems; signal processing; machine learning; biomedical imaging; optimization; proximal optimization; regularization; mathematical modeling; identifiability; likelihood; logconcavity; immunoassays; convolutional coding; functional analysis; abstract inference; learned iterations; unrolled algorithms; Electrical Engineering; Elektro- och systemteknik;

   Sammanfattning : Inverse problems arise in any scientific endeavor. Indeed, it is seldom the case that our senses or basic instruments, i.e., the data, provide the answer we seek. LÄS MER

4. 3. Functional studies of Mediator in Arabidopsis thaliana and Saccharomyces cerevisiae

   Författare :Nils Elfving; Stefan Björklund; Jesper Svejstrup; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transcriptional regulation; chromatin; stress; Pol II; mediator; DREB2A; ZFHD1; MYB-like; Msn2; molekylärbiologi; Molecular Biology;

   Sammanfattning : Mediator has been shown to be essential for regulation of RNA Polymerase II mediated transcription. Mediator functions as an interface between the general transcriptional machinery and a multitude of DNA binding transcriptional regulators, although the molecular mechanism for the process is elusive. LÄS MER

5. 4. Functional Characterization of the Cellular Protein p32 : A Protein Regulating Adenovirus Transcription and Splicing Through Targeting of Phosphorylation

   Författare :Christina Öhrmalm; Göran Akusjärvi; Neus Visa; Uppsala universitet; []
   Nyckelord :Cell and molecular biology; Adenovirus; p32; ASF SF2; E4-ORF4; Splicing; Transcription; CTD; RNA Pol II; Cell- och molekylärbiologi;

   Sammanfattning : Cellular processes involved in the conversion of the genetic information from DNA into a protein are often regulated by reversible phosphorylation reactions. By modulating the phosphorylated status of key proteins their activity can either be enhanced or repressed. LÄS MER

7. 5. Studies of Functional Interactions within Yeast Mediator and a Proposed Novel Mechanism for Regulation of Gene Expression

   Författare :Magnus Hallberg; Stefan Björklund; Karl Ekwall; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Mediator; Transcriptional regulation; Srb10; Cdk8; Med2; Srb7; Med21; RNA pol II; Biokemi; Biochemistry; Biokemi; medicinsk biokemi; Medical Biochemistry;

   Sammanfattning : The yeast Mediator complex is required for transcriptional regulation both in vivo and in vitro and the identification of similar complexes from metazoans indicates that its function is conserved through evolution. Mediator subunit composition and structure is well characterized both by biochemical, genetic and biophysical methods. LÄS MER